First Annual Report of the Henry Phipps Institute for the Study, Treatment, and Prevention of Tuberculosis

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    <title>First Annual Report of the Henry Phipps Institute for the Study, Treatment, and
     Prevention of Tuberculosis</title>
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    <p>Published by the Henry Phipps Institute. 238 Pine Street. Philadelphia. 1905.</p>
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      <title>irst Annual Report of the Henry Phipps Institute for the Study, Treatment, and
       Prevention of Tuberculosis</title>
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       <publisher> Henry Phipps Institute </publisher>
       <date>1905</date>
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   <head>FIRST ANNUAL REPORT OF THE HENRY PHIPPS INSTITUTE FOR THE STUDY, TREATMENT, AND PREVENTION
    OF TUBERCULOSIS A BRIEF ACCOUNT OF THE WORK OF THE FIRST YEAR AND A REPRINT OF THE LECTURES
    DELIVERED UNDER THE AUSPICES OF THE INSTITUTE DURING THE YEAR PUBLISHED BY THE HENRY PHIPPS
    INSTITUTE 238 PINES STREET, PHILADELPHIA TEMPORARY QUARTERS, 238 PINE STREET.</head>
   <head>THE WORK OF THE FIRST YEAR</head>
   <pb n="3"/>
   <!--
    Faithful transcription v. readibility v. functionality (page image linking)
    <p>p. 3</p>-->

   <p>The Henry Phipps Institute was founded on February 1, 1903. It was incorporated September 1,
    1903. The purposes of the Institute as set forth in its charter are: <seg ana="#scipract">“The
     study of the cause, treatment, and prevention of tuberculosis, and the dissemination of
     knowledge on these subjects; the treatment and the cure of consumptives. The benefits shall be
     administered without regard to race, creed, or color.”</seg> The founder of the Institute is
    Henry Phipps, Esq., who also maintains it. Incorporators are Henry Phipps, Esq., Lawrence F.
    Flick, M.D., Mr. Geo. E. Gordon, Miss Amy F. Phipps, and Mr. Samuel Harbison.</p>
   <p>Clinical work was begun in the Phipps Institute in temporary quarters at 238 Pine street,
    Philadelphia, on the second day of February, 1903, the day after foundation. <seg
     ana="#intervention">Dispensary patients were seen on that day and from that day on.</seg> From
    the first day on which work was begun the number of patients exceeded the capacity of the
    Institute for clinical work. Bare floors and walls of the first-story front room, a few chairs,
    a clerk, and three physicians constituted the equipment at the start. Dispensary work and
    fitting up went hand in hand for months. During this time order was brought out of chaos and the
    lines of work were developed, until finally a complete organization was brought into existence.
     <seg ana="#intervention">In the beginning arrangements were made with a drug-store to supply
     medicine and with milkmen to supply milk to patients to whom these articles had to be given
     free.</seg> These were temporary makeshifts until the Institute could create its own machinery
    for supplying these commodities.</p>
   <p>Number 238 Pine street is a well-built, large structure, which</p>
   <pb n="4"/>
   <!--<p>p. 4</p>-->
   <p>had been put up for lodge purposes but had been unoccupied for some years. It is a four-story
    building with a small threestory back building. The back building evidently was an old house
    which had been moved back. The front building is twentysix feet front and sixty-six feet deep
    and the back building is eighteen by thirty-two feet in dimensions. There is a side yard and å
    back yard, the side yard being a narrow strip seven and onehalf by thirty-two feet and the back
    yard an area of twenty-five by thirty-three feet. The front building has high ceilings on each
    floor with fine large windows on two sides on the first floor, and three sides on the second,
    third, and fourth floors. On the first floor there is a hallway with a stairway in the rear and
    two large rooms which, no doubt, were used as reception rooms or parlors. On the second, third,
    and fourth floors of the front building there is, on each, one large room, two small rooms, and
    a stairway landing. In the back building on the first floor there is a very small kitchen, a
    very small dining room, and a back stairway leading to the second floor. On the second floor
    there is one small bedroom and a bathroom with a stairway leading to the third floor. On the
    third floor there is one small bedroom. In the back building all the ceilings are low.</p>
   <p>We divided the front room of the first floor into consultation rooms and an office, and the
    back room into a consultation room, a waiting-room, a <orgName ref="#drugstore">drug-store</orgName>, and a <orgName ref="#labs">laboratory</orgName>.
    <!-- See: the value of these spaces. Drug store &
 lab are important. --> We fitted up the little dining-room in the back building as a
    consultation room, and the little kitchen as an autopsy room. We made wards of the large rooms
    front on the second, third, and fourth floors, and a bathroom and linen room of one of the
    little rooms back on each floor. The other little room on each of the second and third floors we
    fitted up as a <orgName ref="#dietkitchen">diet kitchen</orgName> and that on the fourth floor
    as the kitchen proper. <!-- See: diet kitchen. -->There were platforms on both sides in the
    front and the rear of the three large rooms front. We removed the platforms in the front and the
    rear and retained those on the sides. These were about six inches above the level of the
    floor.</p>
   <pb n="5"/>
   <!--<p>p. 5</p>-->
   <p>We placed eighteen beds in each room on the second and third floors and sixteen in the room on
    the fourth floor. We put a dining table in each of the wards for the patients who are up and
    about and a food carriage to keep the food warm while being served. These three large rooms made
    excellent wards, having high windows on two sides, and a ventilator above a door on the third
    side. We placed three electric fans in each ward to supplement the natural ventilation and also
    to keep the wards cool in summer. We placed a gas range in the little kitchen on the fourth
    floor. This we did as a matter of cleanliness and economy.</p>
   <p>The second floor of the back building we fitted up as a dining-room for the nurses. We lodged
    the nurses temporarily in rented rooms outside. A little corner of the room we fitted up as an
    office for the head nurse. The room on the third floor of the back building we fitted up as a
    sterilizing room and laundry. Opening out from this, we constructed a flat over the bathroom
    below for the purpose of drying clothing, and from this flat we ran lines to a pole at the end
    of the yard as a means of extending the facilities for drying clothes.</p>
   <p>We put steam heat in the building, an electric pump for pumping water to the roof, and new
    plumbing. The back yard and cellar we cemented. We put up canopies in the back yard for the
    protection of patients while sitting out. We transformed the rear cellar into a pathological
    museum and part of the front cellar into a storage room. <note type="editorial"
     rendition="#editorialnote"> They immediately made a museum as part of the institute </note>
    <!-- They immediately made a museum as part of the institute. --> For sanitary reasons we had
    all the walls of the building scrubbed and repainted, all the woodwork thoroughly scrubbed, and
    the cellar walls whitewashed. <seg ana="#autopsy">We put electric lights in the cellar, on the
     fire-escape, and in the autopsy room, as a matter of safety against fire and also as a matter
     of convenience.</seg> For lighting the rest of the building we use gas.</p>
   <p>All of these details about the preparation of the building and the opening of the hospital are
    here given for the purpose of showing <seg ana="#intervention">how inexpensively and easily an
     old building can be</seg></p>
   <p>p. 6</p>
   <p><seg ana="#intervention">transformed into a fairly good modern hospital in a short time, and
     how easy it is in any community to make provision for the treatment of the consumptive poor
     without waiting until a great deal of money is at hand and ideal conditions present
     themselves.</seg> It, moreover, will be of importance to keep all of these matters in mind in
    connection with the results.</p>
   <p>The wards of the hospital were opened on April 20th. It had taken all of this time to put the
    house in condition for the reception of patients. Meanwhile the dispensary service had grown
    very large. When the wards were opened they filled very rapidly -more rapidly, indeed, than was
    desirable, for it was difficult to secure a nursing staff. The fear of tuberculosis materially
    interfered with the organization of a nursing staff. <seg ana="#intervention #multicase">The
     nursing problem was finally solved by opening a training school with girls who had been cured
     at the White Haven Sanatorium. The Institute is thus doing a double good work, that of training
     women for the care of consumptives and that of making an occupation for cured
     consumptives.</seg> The nursing staff at the end of the first year consisted of five trained
    nurses and five pupil nurses.</p>
   <p>As the work increased in the dispensary the medical staff was augmented, and by the time the
    wards were open quite a fairsized staff had been organized. As with the nursing staff, there was
    some difficulty in organizing a medical staff, partly on account of fear of tuberculosis and
    partly, perhaps in a greater degree, on account of the high grade of men needed. Inasmuch as the
    Institute is for the study of tuberculosis as well as for its treatment and prevention, men not
    only of ability, but with preliminary training for original research and advancement of medical
    science had to be selected. At the end of the first year there were sixteen men on the medical
    staff.</p>
   <p>The work accomplished by the Institute during the first year is interesting for its magnitude
    as well as for its scientific and philanthropic worth. Its magnitude in some measure detracts
    from its scientific value, because during the period of organiza-</p>
   <p>p. 7</p>
   <p>tion pressure of work led to inaccuracies of observation and incompleteness of records.
    Besides, men had to be trained for the work, as it was along new lines. <seg ana="#scipract">To
     do exact scientific work in a dispensary was a new departure. It had to be made clear,
     moreover, that the Institute stood for science as well as for charity.</seg> An earnest effort
    was made by all to do good work, and whatever shortcomings occurred grew out of inexperience and
    overwork. <seg ana="#scipract">The magnitude of this first year's work is in a measure indicated
     by the records of cases, which in bound form consist of ten octavo volumes of about one
     thousand pages each. These records are brimful of scientific data, and will form the basis of
     future scientific papers. Some of the data are summarized in this report.</seg></p>
   <p>It has taken much labor of the most painstaking kind to put this first year's records into
    exact order, because of the confusion which grew out of the excessive amount of work always on
    hand during the year. <seg ana="#scipract">From the beginning each patient as he applied for
     treatment was given a number in consecutive order and his name was inscribed on a history sheet
     for examination. At all times there were more patients in the dispensary than could be taken
     care of by the medical and clerical staffs. Sometimes patients were given numbers, but could
     not be reached by the physician, and sometimes the physician in the desire to help as many of
     these poor people as possible allowed sympathy to get the better of science, and gave treatment
     without a complete record. It takes an hour to make a complete scientific record of a patient,
     and with a crush in the waiting-room men gave treatment without a history in the expectation of
     getting leisure to take the history later on when the pressure was less, but such a time never
     came and the history was not taken. This sympathetic interference with the scientific work of
     the Institute finally was checked by creating a waiting list in the dispensary and assigning
     new cases to men only as they could take care of them.</seg></p>
   <p>p. 8</p>
   <p><seg ana="#scipract">Some confusion also grew out of mistakes of the clerical staff. In a few
     instances the same number was given to two patients, and in a few others two numbers were given
     to the same patient returning for treatment unrecognized as having been there before.</seg></p>
   <p><seg ana="#scipract">The records have been put in perfect order and all mistakes have been
     carefully eliminated. Future mistakes are guarded against by our present system of records. All
     patients now are entered numerically in a book and indexed alphabetically in a card index.
     Besides, the history sheets are filed away in numerical order in sections of ten.</seg></p>
   <p><seg ana="#scipract #multicase">The highest numbered history sheet at the end of the year was
     twenty hundred and forty-eight. A careful elimination of all errors shows that twenty hundred
     and thirty-nine patients were treated. Eight patients had received two histories each, two
     patients had received the same number, and two numbers had been skipped.</seg></p>
   <p><seg ana="#multicase">Of the patients treated, two hundred and fifty-four were treated in the
     hospital. Of these, one hundred and eighteen were treated in the dispensary before admission
     into the hospital or after discharge. The number of patients who received treatment in the
     dispensary therefore was nineteen hundred and three.</seg></p>
   <p><seg ana="#multicase">Nine hundred and four dispensary patients made one visit only; some
     because they entered the hospital; some because they were unsuitable; some because they did not
     have tuberculosis; and others because they merely came for an opinion.</seg></p>
   <p><seg ana="#multicase">Of the persons registered for treatment, three hundred and sixty did not
     have tuberculosis, two hundred and fourteen were unsuitable in that they could afford to pay
     for their treatment, and seven had no diagnosis recorded. In all, therefore, fourteen hundred
     and fifty-eight poor people with tuberculosis applied for treatment.</seg></p>
   <p><seg ana="#multicase">In the dispensary nine hundred and ninety-nine patients made more than
     one visit. These made a total of six thousand eight hundred and seventy-six visits, or an
     average of six and eighttenths visits each. The entire number of visits made in the dispensary
     was seven thousand seven hundred and eighty-one.</seg></p>
   <p>p. 9</p>
   <p><seg ana="#multicase">Of the patients admitted into the hospital, two hundred and forty-five
     had tuberculosis; seven had no diagnosis recorded; one was recorded as having bronchitis, and
     one was undiagnosed.</seg>
    <seg ana="#casestudy #opacity1">One patient who had been diagnosed as having tuberculosis was
      <seg ana="#autopsy">found on autopsy also to have had bronchiectasis.</seg> This patient is
     made the subject of a special report. The patient who was recorded as having bronchitis
     remained in the hospital only twelve days. This diagnosis was not scientifically established.
     The probabilities are that the patient had tuberculosis.</seg>
    <seg ana="#casestudy">One of the seven patients of whom no diagnosis was recorded, <seg
      ana="#autopsy opacity2">was diagnosed as having tuberculosis at autopsy. She died one-half
      hour after admission.</seg></seg>
    <seg ana="#multicase">The other six left the hospital before a diagnosis could be made. The two
     hundred and fifty-four patients spent twelve thousand and sixty-eight days in the hospital,
     averaging forty-eight and seven hundredths days each. Forty patients were in the hospital less
     than one week. Of these, ten died and the others left for various reasons. The longest stay of
     any patient was two hundred and eighty-six days. This patient was in the hospital at the end of
     the year. He was a most advanced case when he came in, but had steadily improved.</seg></p>
   <!--Consider ignoring the table content altogether unless you want to semantically tag any of the table values.
    I would include an XML comment like this in the TEI to indicate that a table was printed in the text.-->
   <p><seg ana="#table">NATIVITY</seg></p>
   <p>p. 10</p>
   <p><seg ana="#table">NATIVITY.—(Continued) </seg></p>
   <p><seg ana="#table">MIXE PARENTAGE </seg></p>
   <p>p. 11</p>
   <p><seg ana="#table">MIXED PARENTAGE.—(Continued.) </seg></p>
   <p><seg ana="#multicase">Nearly one-half of all patients registered were foreign-born.</seg> The
    foreign-born males exceeded the foreign-born females about 19 %. Many of the foreign-born have
    been in the country so short a time that it may be assumed they had the disease when they landed
    on our shores.</p>
   <p>It is interesting to note the places from which the foreign-born patients came. Russia
    supplied us the greatest number in the first generation, Ireland the next greatest number, and
    Germany the next. Going one generation back, Ireland changes places with Russia. In a measure
    the number of cases from the various countries is in ratio with the immigration from those
    countries. Russia is sending us the largest number of immigrants in the immediate generation and
    Ireland sent us the largest number in the past generation. The racial element in these
    statistics unfortunately is incomplete. It would have been interesting to have singled out the
    Jews with a view of throwing light upon the question of immunity. In future this will be done.
    The majority of the patients from Russia, Roumania, Austro-Hungary, and Poland, however, were
    Jews. <note type="editorial" rendition="#editorialnote"> Racial science is prominent in this
     kind of discussion. Explicitly, they are talking about Jewish people </note>
    <!-- Racial science is prominent in this kind of discussion. Explicitly, they are talking about Jewish people.--></p>
   <p><seg ana="#table">Age </seg></p>
   <p>p. 12</p>
   <p><seg ana="#multicase">More than one-half of the patients registered for treatment were of the
     age which is of the greatest importance to the public weal. </seg>During the age-period between
    twenty and forty, men and women not only are of greatest value as producers of wealth, but are
    important factors in the propagation of the species. Death during this life-period is a serious
    blow to the public weal. It not only strikes at the source of wealth, but also puts a drag on
    the public weal in the production of dependent orphans. Most people who die between twenty and
    forty leave behind them dependent children, and inasmuch as tuberculosis is a longdrawn-out
    disease, dependent children who have been made orphans by this disease are apt to become public
    charges.<!-- This is wild. The value of the
 population is defined in relation to the economic value and in eugenicist assunmptions of the
 continuiation of the species. --></p>
   <p><seg ana="#table">SEX. Male,1179 Female,851 No Record,9</seg></p>
   <p><seg ana="#multicase">The number of males greatly exceeds the number of females.</seg> This is
    probably due in part to the foreign element. <!-- More racism and xenophobia --> This
    preponderance cannot be accepted as an index of respective liability of the sexes to
    tuberculosis.</p>
   <p><seg ana="#table">COLOR. </seg></p>
   <p>The vast preponderance of white people over colored people among the patients registered is no
    indication of the relative amount of tuberculosis in the races, nor of their relative poverty.
    The colored people are much more prone to tuberculosis than are the white people. There probably
    is as much poverty among the colored people as among the whites. The colored people, however,
    are more loath to become a public charge and are more disposed to help themselves. They will not
    go into a public institution if they can manage to crawl around. <!-- What the fuck. -->
    <seg ana="#multicase">The proportion of colored admissions to white admissions, however,
     was</seg></p>
   <p>p. 13</p>
   <p><seg ana="#multicase">greater than is the proportion of the colored population to the white
     population in Philadelphia. The number of colored admissions was about 6 1/2% of the white
     admissions.</seg></p>
   <p><seg ana="#table">RESIDENCE </seg></p>
   <p><seg ana="#multicase">As will be seen from the table, vastly the majority of the patients were
     from Philadelphia.</seg><seg ana="#scipract"> A reference to the map published as a part of
     this report, which gives the location of patients in the city of Philadelphia, will show that
     the majority of the patients came from the immediate vicinity of the Institute.</seg> The
    Institute is located in the poorest district of Philadelphia, and quite naturally a great deal
    of tuberculosis exists in this district. This map, however, cannot be accepted as an indication
    of the prevalence of tuberculosis in Philadelphia. The probabilities are that the disease is
    fully as prevalent in the mill districts of the city.</p>
   <p><seg ana="#table">SOCIAL CONDITION</seg></p>
   <p>There are two elements in the statistics of the social condition of the patients worthy of
    notice: <seg ana="#multicase opacity1"><seg ana="#opacity2">one the number of married people,
      and the other the number of widowed.</seg> Forty per cent. of the patients who applied for
     assistance were married and consequently destined, unless the disease could be arrested, to
     leave orphaned children and widowed consorts. </seg>Inasmuch as the poverty of these poor
    people is distressing, it is to be anticipated that unless restored to health they will almost
    necessarily become a public charge. <seg ana="#multicase">It is remarkable that nearly nine per
     cent. of the applicants were already widowed. What a sad picture of distress and sorrow can be
     conjured up out of these figures!</seg></p>
   <p>p. 14</p>
   <p><seg ana="#table">OCCUPATION </seg></p>
   <p>p. 15</p>
   <p><seg ana="#table">OCCUPATION.-(Continued.) </seg></p>
   <p>p. 16</p>
   <p><seg ana="#table">OCCUPATION.-(Continued.) </seg></p>
   <p>In the occupations of those who applied for treatment some very interesting points present
    themselves. <seg ana="#scipract">For a correct interpretation of occupation statistics one needs
     to keep in mind such factors as the remuneration which goes with the occupation, the severity
     of the labor involved, the propensities to alcoholism, the presence of irritating substances in
     the air of places of employment, and the relative number of people employed in the
     occupation.</seg> The occupation from which the highest number came for treatment at the Phipps
    Institute during the year is housework. In this connection it must be borne in mind that among
    the poor all married women and most widows give their occupation as housework. The wife and
    mother is most intensely</p>
   <p>p. 17</p>
   <p>exposed to contagion in a household in which there is tuberculosis. It is not a matter for
    surprise, then, that of the women who apply for charity in the treatment of tuberculosis nearly
    one-half are houseworkers. <seg ana="#multicase #opacity1">The number of women who applied for
     treatment is eight hundred and fifty-one and the number of houseworkers is three hundred and
     sixty. The other female occupations most numerously represented in the table are, in respective
     order: factory hand, forty-seven; weaver, thirty-two; seamstress, thirty-three; laundry-worker,
     fourteen; store employee, twelve; and nurse, seven. Some of these occupations are pursued by
     men as well as women. The occupation of seamstress is the only one exclusively filled by women.
     With this occupation the question of remuneration plays a part. Seamstresses are poorly paid
     and are compelled to work in unhygienic environments.</seg></p>
   <p>The male occupation which stands at the head of the list is that of laborer, with one hundred
    and one. The laborer is not only poorly paid, and consequently poorly fed, but lives in poor
    environments. He has more chance of having the disease in his home than most people, by reason
    of his poverty, and consequently he is more apt to be exposed to contagion than most people.
     <seg ana="#multicase #opacity1">A group of occupations all belonging to the same category is
     that of tailor with fifty-nine; that of clerk with forty-three; that of cigarmaker with thirty;
     that of salesman with thirteen; that of printer with fourteen; and that of shoemaker with
     twelve</seg>. In all of these occupations there is poor pay, which means deprivation at home,
    and bad sanitary conditions in the place of occupation. Another group is that in which alcohol
    plays a part; those occupations in which, by reason of association, exposure, or hard work,
    there is a temptation to use alcohol in some form or other. <seg ana="#multicase #opacity1">To
     this group belongs the occupation of driver with forty-two; that of waiter with twenty-one;
     bartender with fourteen; plumber with ten; and cook with ten.</seg> In these occupations
    neither want of food nor lack of fresh air plays a part. There is usually plenty to eat and
    there is either outdoor life or fair indoor</p>
   <p>p. 18</p>
   <p>environment. The propensity to tuberculosis in these cases is due to alcoholism. In these
    occupations the temptation and opportunity for the use of alcohol are great. Another group is
    that in which occupation exposes to inhalation of irritating substances given off in
    manufacturing processes. These irritating substances may act in two ways, one as a medium of
    contagion, the other as a means of traumatism. They probably act in both ways. <seg
     ana="#multicase #opacity1">To this group belongs the occupation of mill-hand with sixty-four;
     machinist with thirty-five; weaver with thirty-two; iron-worker with twenty-one; upholsterer
     with nine; and leatherworker with nine</seg>. The high morbidity in some of the occupations is
    only intelligible upon the assumption that the occupations were taken up after the disease had
    been contracted, because the occupations are easy and out-of-doors. Such are, for example, the
    occupations of canvasser, agent, collector, and peddler. The occupation of car conductor, I
    know, is frequently taken up by persons who have had tuberculosis and who have made a partial
    recovery.</p>
   <p><seg ana="#table">ALCOHOLISM</seg></p>
   <p>In former times alcohol was looked upon as a preventive and cure of tuberculosis. At the
    present day alcohol is looked upon as a predisposing cause of the disease and as an impediment
    to recovery. Neither of these views apparently gets much support from the statistics here given.
    The word “alcoholism" as here used means an excessive use of alcohol, but not necessarily a use
    of alcohol to the degree of drunkenness. A person was not put down as an alcoholic unless he
    used enough alcohol to do himself some physical harm. Of course, it is not easy to get a history
    of alcoholism from a patient, and some allowance must be made on this score for the smallness of
    the numbers. As the figures stand, however, the percentage of alcoholics among consumptives and
    among the relatives of consumptives does not</p>
   <p>p. 19</p>
   <p>seem to differ very much from that of nonconsumptives and relatives of nonconsumptives.</p>
   <p><seg ana="#table">PREDISPOSING DISEASES.</seg></p>
   <p>It has been held that certain diseases greatly predispose to tuberculosis. This view has
    originated from the observation that these diseases frequently precede tuberculosis within a few
    years, and sometimes within a few months. The diseases which have best earned this reputation
    are typhoid fever, pneumonia, and pleurisy. The figures would seem to indicate that pleurisy
    most frequently precedes tuberculosis, pneumonia next, and typhoid fever last. More than
    one-half the cases were preceded by one or the other of these diseases. There is good reason to
    believe that the pleurisies, pneumonias, and typhoid fevers which precede tuberculosis
    frequently are tuberculosis which goes unrecognized and simulates the diseases named. Some
    observers even claim that practically all pleurisies are tuberculous. That irregular forms of
    pneumonia and typhoid fever often are tuberculosis cannot be doubted.</p>
   <p><seg ana="#table">SOURCE OF CONTAGION.</seg></p>
   <p>p. 20</p>
   <p>An earnest effort has been made in history-taking to discover the source of contagion of each
    case. In the majority of cases this was made out to the extent, at least, of finding a known
    source of contagion. In many cases, however, owing to the ignorance and prejudice of patients
    and their inability to understand and speak the English language, it was impossible to get a
    satisfactory history. The histories of exposure to contagion which could be gotten emphasize in
    a striking manner the part which family relationship plays in the spread of tuberculosis. With
    this picture before one, it is easy to understand why the ancients looked upon tuberculosis as
    an inherited disease. <seg ana="#multicase">More than two-thirds of the cases in which a history
     of exposure to contagion could be obtained gave contagion from blood relatives as the source of
     the disease. The number of cases in which the disease was derived from consorts or from members
     of their families is surprisingly large, and the number of cases which gave fellowemployees and
     infected houses as the source of contagion is surprisingly small.</seg> Of course, it must not
    be lost sight of that family contagion is always the most evident and easily recognized and that
    the large number of cases in which the source of contagion remained undiscovered were in all
    probability cases of occupation and house contagion. These forms of contagion are sometimes
    difficult to ferret out even with intelligent observing people, because one cannot always know
    when he is working with a consumptive or when the home into which he moves has been occupied by
    a consumptive.<seg ana="#multicase"> Some of the patients gave histories of double and even
     triple exposure.</seg></p>
   <p><seg ana="#table">PLACE OF BEGINNING OF TUBERCULOSIS OF THE LUNGS.</seg></p>
   <p>p. 21</p>
   <p>An effort has been made to determine in what part of the lungs the disease began. The
    conclusions here recorded were reached by trying to determine on which side the disease had made
    the greatest ravages. The side which had the most extensive lesion was recorded as the side on
    which the disease began. This cannot always be accepted as a safe deduction. Neither can it be
    said that the observations upon which these records are based are entirely reliable. The
    records, however, strongly support the universally accepted view that the right lung is most
    frequently the first affected.</p>
   <p><seg ana="#table">TISSUE INVOLVED.</seg></p>
   <p>A fair picture of the stages of tuberculosis in which patients applied for treatment is
    presented in this table. The picture is underdrawn rather than overdrawn. In the beginning of
    the service incomplete records were made. <seg ana="#multicase">Of the dispensary patients more
     than one-half had both lungs involved and about onethird were far advanced in the disease. <seg
      ana="#opacity1">Of the hospital patients only a little over 7 % had the disease limited to one
      lung.</seg></seg> All this shows how slow people with tuberculosis are to recognize that they
    are ill and need medical attendance. Tuberculosis is such an insidious disease that it makes
    great progress before its existence is even suspected by the victim.</p>
   <p><seg ana="#table">FREEDOM FROM COUGH.</seg></p>
   <p>p. 22</p>
   <p>It is usually taken for granted that cough is an essential symptom of pulmonary tuberculosis.
    Cough is a usual symptom, but not an essential one. It may be absent in tuberculous patients and
    it may be present in nontuberculous patients. <seg ana="#multicase #opacity1">Forty-one patients
     who were diagnosed as having tuberculosis were free from cough.</seg> At rest, with proper
    regulation of diet, tuberculous patients cough very little. In the hospital no cough medicines
    are used, and although the patients all are advanced, many with both lungs extensively diseased,
    there is very little coughing.</p>
   <p><seg ana="#table">TUBERCLE BACILLI IN SPUTUM.</seg></p>
   <p><seg ana="#scipract">Many sputum examinations were not recorded. This was on account of the
     constant pressure of work. Of the cases recorded, a little less than two-thirds showed the
     presence of tubercle bacilli in a limited number of examinations.</seg> This gives a fair
    picture of the frequency with which sputum of tuberculous patients is negative. <seg
     ana="#scipract">One or two examinations, when negative, mean very little. Tubercle bacilli may
     be absent from the sputum upon repeated examinations even in advanced cases. <seg
      ana="#autopsy">This was demonstrated in some of the cases which came to autopsy.</seg> A
     negative report on sputum, even when repeated examinations have been made, should not be
     allowed to stand against positive clinical evidence of tuberculosis in making a diagnosis. It
     is only when the clinical symptoms agree with the negative report of the sputum that a negative
     diagnosis should be
    made.</seg><!-- This is an excellent example of the difficulties with diagnosis --></p>
   <p><seg ana="#table">HOARSENESS.</seg></p>
   <p>p. 23</p>
   <p>Hoarseness in tuberculosis is not necessarily an indication of laryngeal tuberculosis even
    when the hoarseness is persistent. Usually persistent hoarseness does mean laryngeal
    tuberculosis. Tuberculosis of the pharynx and tonsils occurs pretty often in advanced stages of
    the disease and sometimes accounts for persistent hoarseness. Mixed infection alone may be
    responsible for this symptom, however. Chronic catarrhal rhinitis and pharyngitis occur
    frequently in tuberculosis and sometimes keep up hoarseness for a long time.</p>
   <p><seg ana="#table">DISEASES OF THE CIRCULATORY SYSTEM.</seg> These statistics upon lesions and
    functional diseases of the circulatory system, it must be admitted, cannot be accepted as giving
    an accurate picture of the frequency with which such conditions occur in tuberculosis. It
    requires great skill and large clinical experience to make exact trustworthy records of organic
    heart lesions. <seg ana="#scipract">Such skill and experience cannot be claimed for the medical
     staff in the beginning of the work, at least. In many cases, moreover, no record was made at
     all of the condition of the circulatory system.</seg> Even in the matter of functional disturb- </p>
   <p>p. 24</p>
   <p>ances, such as accentuated second sound, the record is very incomplete. Some of the members of
    the staff recorded accentuated second sound in a majority of the patients and others recorded it
    in almost none. Neither was there always a distinction made between accentuation of the aortic
    second sound and the accentuation of the pulmonic second sound. <seg ana="#scipract">This kind
     of work is more accurately done now than it was in the beginning, so that future statistics
     will throw more light upon the subject.</seg></p>
   <p><seg ana="#table">URINARY ABNORMALITIES.</seg></p>
   <p><seg ana="#scipract">Although it is part of the program of the Institute to make a careful
     urinary analysis of all patients who apply for treatment, little was accomplished in this line
     during the first year. Many examinations which were made were not recorded, and there is no way
     of determining the number of cases on which this table is based. Our shortcomings were due
     principally to the heavy pressure under which we have worked from the beginning and to the lack
     of facilities for such work.</seg></p>
   <p><seg ana="#table">GENITO-URINARY DISEASE.</seg></p>
   <p><seg ana="#scipract">The statistics here given, it must be frankly admitted, are unreliable.
     In many cases the thorough investigation necessary for determining whether or not there was
     genito-urinary involvement was not made.</seg> It is not an easy matter to determine clinically
    whether or not such organs are tuberculous. The symptoms which may indicate genito-urinary
    tuberculosis may also</p>
   <p>p. 25</p>
   <p>indicate other diseases, and it is sometimes impossible to differentiate. Besides, in the
    cases in which genito-urinary disease is recorded there is no record as to whether or not the
    genito-urinary diseases were tuberculous in character.</p>
   <p><seg ana="#table">HEMOPTYSIS.</seg></p>
   <p>It is rather surprising that so large a percentage of cases gave a history of hemoptysis. This
    same ratio probably would not hold with people better situated in life. Hemoptysis undoubtedly
    is largely due to overexertion. The pulmonary circulation becomes embarrassed by reason of
    obstruction and the heart is stimulated to greater effort. Bodily fatigue adds to this
    overaction, and with contraction of the blood-vessels hemorrhage The patients who entered the
    hospital and were placed at rest remained almost free from hemorrhages even in the advanced
    stages.</p>
   <p><seg ana="#table">NIGHT-SWEATS.</seg></p>
   <p><seg ana="#multicase">In practically all of the patients in the hospital the nightsweats
     stopped after the patient had been at rest for awhile and had had his diet regulated.</seg> No
    drugs are used in the hospital for night-sweats and none are necessary. <seg ana="#multicase"
     >The large number of cases with night-sweats both in the hospital and dispensary indicates how
     advanced many of the patients were when they came under treatment. It also shows how few
     patients with tuberculosis come under treatment early.</seg></p>
   <p>p. 26</p>
   <p><seg ana="#table">DIARRHEA.</seg></p>
   <p><seg ana="#multicase opacity1">Of the patients with persistent diarrhea, fifty were in the
     hospital.</seg> Persistent diarrhea in a tuberculous patient usually indicates that the patient
    has tuberculous ulceration of the bowels. Sometimes, however, extensive ulceration of the bowels
    exists without much disturbance of the bowels; and sometimes great disturbance of the bowels
    exists without ulceration.</p>
   <p><seg ana="#table">EDEMA.</seg></p>
   <p>Edema in tuberculosis usually is the result of damaged circulation following in the wake of
    the tuberculous process in the lungs and other organs. Right-sided dilatation of heart with
    consequent dilatation of the left heart occurs frequently in advanced tuberculosis. This no
    doubt plays a part in edema. Tuberculosis of the kidneys, however, probably also plays a part.
    The kidneys frequently become the seat of tuberculosis. <seg ana="#scipract">The records as
     given here probably understate the percentage of cases in which edema occurs in tuberculosis.
     In many cases no careful investigation was made for edema and no records were kept.</seg></p>
   <p><seg ana="#table">DURATION OF DISEASE.</seg></p>
   <p><seg ana="#scipract">The records here given understate the actual duration of the
     disease.</seg> It takes considerable experience to be able to bring</p>
   <p>p. 27</p>

   <p>out the full duration of tuberculosis when taking the history of a case. <seg ana="#scipract"
     >In our first year's work there has been a continuous increase in the duration of disease as
     the experience of our men grew in taking histories.</seg>
    <seg ana="#multicase">Patients, as a rule, fix the beginning of the disease by the first severe
     break in health.</seg> As a matter of fact, the beginning of tuberculosis gives no symptoms.
    Very often even a number of serious interferences with health, recurring at intervals of three
    to six months, may take place before suspicion points to what is the matter. Tuberculosis exists
    from the time of implantation, and the duration of the disease really should be counted from the
    time of exposure to contagion.</p>
   <p><seg ana="#table">WEIGHT.<!-- $$$FIGURE OUT THIS TABLE --></seg></p>
   <p>The weights given in this table are net weights. <seg ana="#scipract">When a patient gained
     and then lost, only that which he held was counted; and when a patient lost and then gained,
     only the gain above</seg></p>
   <p>p. 28</p>
   <p><seg ana="#scipract">what he weighed when he began treatment was counted. In the same way the
     losses were based upon the weight when treatment began.</seg></p>
   <p>Weight is a criterion of the progress of tuberculosis up and down. Loss of weight undoubtedly
    is one of the results of tuberculous toxemia. One of the first evidences of deterioration is
    loss of weight. An early sign of improvement in a tuberculous patient, on the other hand, is
    gain in weight. While this is the rule, there are exceptions. Tuberculosis may terminate fatally
    without emaciation. A person with tuberculosis may be so fed up as to become quite rounded and
    well filled out and still go on to death. In these cases death is usually due to complications
    of one kind or another. Sometimes so many organs have been damaged by the tuberculous process
    that life is snuffed out by a simple cold. This is especially true when the kidneys are
    extensively diseased.</p>
   <p>Both in the dispensary and in the hospital there were some very large gains. Along with these
    gains went general improvement and progress toward recovery. <seg ana="#multicase opacity1">The
     highest gain in the hospital was thirty-three and one-half pounds. The greatest loss in the
     hospital was twenty-five and three-quarter pounds. The highest gain in the dispensary was
     thirty-nine pounds and the greatest loss in the dispensary was thirty and one-quarter
     pounds.</seg></p>
   <p><seg ana="#table">RESULTS OF TREATMENT.</seg></p>
   <p>The word improved is here used to indicate any amelioration of symptoms with increase in
    weight and gain in physical health--</p>
   <p>p. 29</p>
   <p>one or both. The improvement in some cases was very marked, and this applies even to advanced
    cases. <seg ana="#multicase #scipract">Some of the patients who came into the hospital as
     advanced cases were restored to a condition of physical health which enabled them to return to
     their occupations. Unimproved includes all cases in which there was no perceptible progress
     toward recovery. Even patients who gained weight for awhile and lost it again, were recorded as
     unimproved. The cases recorded as unimproved sometimes were lost sight of, either by removal
     from the hospital or by giving up treatment at the dispensary. Many of them no doubt died. The
     record of deaths in the dispensary, and in a less degree in the hospital, for this reason, has
     little value.</seg></p>
   <p>SPECIAL WORK.</p>
   <p><seg ana="#scipract">For the purpose of studying tuberculosis from every possible point of
     view and giving relief in all forms of the disease, special departments have been established
     in the Institute and others will be established as the work develops. Up to the present time
     there have been organized a neurological staff, a laryngological staff, and a dermatological
     staff. The laboratory, both in its bacteriological department and in its pathological
     department, has been established and partly equipped, but not fully organized.
     <!-- Laboratory development, specifying
 bacteriology. -->A consulting ophthalmologist has been appointed on the staff. Separate
     reports on laryngological and neurological work are made by Drs. Geo. B. Wood and D. J.
     McCarthy. Dr. Joseph Walsh reports upon the autopsies and Dr. M. P. Ravenel upon a case of
     fibroid phthisis. Drs. H. R. M. Landis and J. W. Irwin report special work assigned by the
     medical director.</seg></p>
   <p>PREVENTION OF TUBERCULOSIS.</p>
   <p><seg ana="#scipract">One of the objects of the Institute is the prevention of tuberculosis.
     What has been accomplished during the year in this direction cannot be recorded, because it
     cannot be measured.</seg>
    <seg ana="#multicase">The patients who have been taken into the hospital have been taken out of
     squalid, poverty-stricken homes, where they had</seg></p>
   <p>p. 30</p>
   <p><seg ana="#multicase">been sources of danger to others.</seg> The probabilities are that every
    removal of such a patient has been the means of preventing at least one implantation. Even when
    the patient returned again to his home, something had been accomplished, because he went home
    trained in preventive measures. <!-- $$$check above for #hygiene tags -->
    <seg ana="#intervention #hygiene">All the dispensary patients are taught and drilled in
     preventive measures. As each patient comes into the waiting-room he is handed a spit-cup, and
     during his stay is taught to use it. When he goes away he is given a tin spit-cup holder, a
     bundle of paper cups, and a bundle of paper napkins and paper bags to take home with him. He is
     also given a set of rules on a large cardboard to hang up in his house, and on a folder to
     carry in his pocket. Every time he comes back to the dispensary he is given a new supply of
     preventive measure material, and is further instructed in its use. At regular intervals he is
     visited in his home by a pupil nurse and is given such instruction and assistance as he may
     need for prevention of the spread of the disease.</seg></p>
   <p>FOOD.</p>
   <p><seg ana="#intervention #hygiene">In the hospital all patients are placed upon a carefully
     selected diet. This consists of milk, eggs, and plain nutritious food. As a rule, patients take
     three quarts of milk and six raw eggs a day and one meal of solid food. This meal consists of
     beef or mutton, fresh vegetables, and fruit. To the dispensary patients milk is served at their
     homes from the Institute wagon or through milkmen. In the beginning all milk was served through
     milkmen. This system of serving through milkmen was not found satisfactory, first because the
     Institute could not control the quality of the milk, and secondly because the system was open
     to fraud. As an experiment the Institute has equipped a milk wagon of its own.</seg></p>
   <p>MEDICINE.</p>
   <p><seg ana="#intervention">To the house patients all medicine is furnished free. To the
     dispensary patients it is furnished either free or at a nominal</seg></p>
   <p>p. 31</p>
   <p><seg ana="#intervention">cost. A nominal charge, consisting of twenty-five cents for one
     prescription, forty cents for two prescriptions, and fifty cents for three or more
     prescriptions to one and the same person at the same time, is made to such patients as can
     afford it, for two reasons: first, to give them a semblance of independence; and, secondly, to
     discourage as far as possible unnecessary drugtaking. <seg ana="#multicase">The majority of
      dispensary patients are, however, unable to maintain even this little pretense of
      self-support.</seg></seg></p>
   <p>SCIENTIFIC RESEARCH.</p>
   <p><seg ana="#scipract">The study of tuberculosis is one of the purposes of the Institute. For
     this reason a laboratory and pathological museum and an autopsy room have been equipped.
    </seg>In the crowded, cramped quarters of the Institute in its temporary home, it has been
    difficult to carry out this purpose. Something has been accomplished, however. <seg
     ana="#multicase #autopsy #scipract">Nearly all patients who have died have been carefully
     autopsied; a valuable collection of pathological specimens has been collected; many sections
     have been made for microscopic study, and a beginning has been made in laboratory research. The
     staff meets weekly for scientific discussion and exchange of thought. All work done is
     carefully scrutinized and criticized at these
    meetings.</seg><!-- Anatomical museum and autopsy. --></p>
   <p>EDUCATIONAL WORK.</p>
   <p>Early in the Institute's first year an international lecture course on tuberculosis was got up
    for the education of the public. Prominent workers from different parts of the world were
    brought to Philadelphia to speak to the world from a Philadelphia platform. The lectures
    delivered on these occasions were published in the medical journals and in abstract in the daily
    papers. They are republished as part of this first annual report, although all of them were not
    delivered within the first year.</p>
   <p>The lecturers were Drs. E. L. Trudeau, of Saranac; Wm. Osler, of Baltimore; G. Sims Woodhead,
    of Cambridge, England;</p>
   <p>p. 32</p>
   <p>Herman M. Biggs, of New York; and Edoardo Maragliano, of Italy. Dr. Trudeau, the pioneer
    worker in the field of tuberculosis in America, opened the course. He was followed by the other
    gentlemen in the order named. Dr. Maragliano was prevented from coming to America at the last
    moment by serious personal illness, but his paper was read at the time set for his appearance
    and was subsequently published. The course of lectures was well attended and the publication of
    the lectures has stimulated much activity in the warfare against the disease. On the occasion of
    Dr. Maragliano's lecture the National Association for the Study and Prevention of Tuberculosis
    was organized.</p>
   <p>THE FIRST YEAR'S HARVEST.</p>
   <p>To organize a new work is a difficult undertaking. The Henry Phipps Institute for the Study,
    Treatment, and Prevention of Tuberculosis is in its conception and establishment an embodiment
    of a new idea-namely, concentrated effort upon a single disease for its extermination. The
    financial resources were at hand through the generosity of Mr. Henry Phipps, but there was no
    precedent for the creation of machinery and the formation of the line of battle. Everything had
    to be worked out and tested. Classical prejudices of all kinds and complexions stood in the way.
    The line of action lay in opposition to preconceived notions and the teaching of medicine for
    generations. Weighed in the balance of these difficulties, the harvest of the first year's labor
    has been good. <!-- Harvest metaphor is so interesting. --> In addition to what has been
    accomplished in treatment, prevention, and education, there has been some golden fruit in the
    training of medical experts and special nurses. This perhaps is the best of the Institute's
    work. The training of women for the care of tuberculous subjects and the creation of a new field
    of labor for women who have had tuberculosis and have recovered, perhaps, would be worth the
    labor and money which have been expended. These women become missionaries in the crusade against
    tuberculosis.</p>
   <p>LAWRENCE F. FLICK.</p>
  </body>
 </text>
</TEI>
First Annual Report of the Henry Phipps Institute for the Study, Treatment, and Prevention of Tuberculosis

Published by the Henry Phipps Institute. 238 Pine Street. Philadelphia. 1905.

irst Annual Report of the Henry Phipps Institute for the Study, Treatment, and Prevention of Tuberculosis Henry Phipps Institute 1905
This refers to any moment a patient is being referred to within the text. This refers to any moment a patient's biometrics, symptoms, or individual life is described. Anything that could be drawn to identify this subject is included. Mention of an autopsy performed Whenever a case study is mentioned. Information about scientific practices, usually related to actions employed during research. Description of multiple cases at once, or talking in the aggregate about the progression of the disease. When a doctor prescribes or does something to cure the patient. A table found in the information. (This has been formatted from the original OCR'd text.) background-color: #cccccc; font-color: #666666;
Commentary on racial science. FIRST ANNUAL REPORT OF THE HENRY PHIPPS INSTITUTE FOR THE STUDY, TREATMENT, AND PREVENTION OF TUBERCULOSIS A BRIEF ACCOUNT OF THE WORK OF THE FIRST YEAR AND A REPRINT OF THE LECTURES DELIVERED UNDER THE AUSPICES OF THE INSTITUTE DURING THE YEAR PUBLISHED BY THE HENRY PHIPPS INSTITUTE 238 PINES STREET, PHILADELPHIA TEMPORARY QUARTERS, 238 PINE STREET. THE WORK OF THE FIRST YEAR

The Henry Phipps Institute was founded on February 1, 1903. It was incorporated September 1, 1903. The purposes of the Institute as set forth in its charter are: “The study of the cause, treatment, and prevention of tuberculosis, and the dissemination of knowledge on these subjects; the treatment and the cure of consumptives. The benefits shall be administered without regard to race, creed, or color.” The founder of the Institute is Henry Phipps, Esq., who also maintains it. Incorporators are Henry Phipps, Esq., Lawrence F. Flick, M.D., Mr. Geo. E. Gordon, Miss Amy F. Phipps, and Mr. Samuel Harbison.

Clinical work was begun in the Phipps Institute in temporary quarters at 238 Pine street, Philadelphia, on the second day of February, 1903, the day after foundation. Dispensary patients were seen on that day and from that day on. From the first day on which work was begun the number of patients exceeded the capacity of the Institute for clinical work. Bare floors and walls of the first-story front room, a few chairs, a clerk, and three physicians constituted the equipment at the start. Dispensary work and fitting up went hand in hand for months. During this time order was brought out of chaos and the lines of work were developed, until finally a complete organization was brought into existence. In the beginning arrangements were made with a drug-store to supply medicine and with milkmen to supply milk to patients to whom these articles had to be given free. These were temporary makeshifts until the Institute could create its own machinery for supplying these commodities.

Number 238 Pine street is a well-built, large structure, which

had been put up for lodge purposes but had been unoccupied for some years. It is a four-story building with a small threestory back building. The back building evidently was an old house which had been moved back. The front building is twentysix feet front and sixty-six feet deep and the back building is eighteen by thirty-two feet in dimensions. There is a side yard and å back yard, the side yard being a narrow strip seven and onehalf by thirty-two feet and the back yard an area of twenty-five by thirty-three feet. The front building has high ceilings on each floor with fine large windows on two sides on the first floor, and three sides on the second, third, and fourth floors. On the first floor there is a hallway with a stairway in the rear and two large rooms which, no doubt, were used as reception rooms or parlors. On the second, third, and fourth floors of the front building there is, on each, one large room, two small rooms, and a stairway landing. In the back building on the first floor there is a very small kitchen, a very small dining room, and a back stairway leading to the second floor. On the second floor there is one small bedroom and a bathroom with a stairway leading to the third floor. On the third floor there is one small bedroom. In the back building all the ceilings are low.

We divided the front room of the first floor into consultation rooms and an office, and the back room into a consultation room, a waiting-room, a drug-store, and a laboratory. We fitted up the little dining-room in the back building as a consultation room, and the little kitchen as an autopsy room. We made wards of the large rooms front on the second, third, and fourth floors, and a bathroom and linen room of one of the little rooms back on each floor. The other little room on each of the second and third floors we fitted up as a diet kitchen and that on the fourth floor as the kitchen proper. There were platforms on both sides in the front and the rear of the three large rooms front. We removed the platforms in the front and the rear and retained those on the sides. These were about six inches above the level of the floor.

We placed eighteen beds in each room on the second and third floors and sixteen in the room on the fourth floor. We put a dining table in each of the wards for the patients who are up and about and a food carriage to keep the food warm while being served. These three large rooms made excellent wards, having high windows on two sides, and a ventilator above a door on the third side. We placed three electric fans in each ward to supplement the natural ventilation and also to keep the wards cool in summer. We placed a gas range in the little kitchen on the fourth floor. This we did as a matter of cleanliness and economy.

The second floor of the back building we fitted up as a dining-room for the nurses. We lodged the nurses temporarily in rented rooms outside. A little corner of the room we fitted up as an office for the head nurse. The room on the third floor of the back building we fitted up as a sterilizing room and laundry. Opening out from this, we constructed a flat over the bathroom below for the purpose of drying clothing, and from this flat we ran lines to a pole at the end of the yard as a means of extending the facilities for drying clothes.

We put steam heat in the building, an electric pump for pumping water to the roof, and new plumbing. The back yard and cellar we cemented. We put up canopies in the back yard for the protection of patients while sitting out. We transformed the rear cellar into a pathological museum and part of the front cellar into a storage room. 1 They immediately made a museum as part of the institute For sanitary reasons we had all the walls of the building scrubbed and repainted, all the woodwork thoroughly scrubbed, and the cellar walls whitewashed. We put electric lights in the cellar, on the fire-escape, and in the autopsy room, as a matter of safety against fire and also as a matter of convenience. For lighting the rest of the building we use gas.

All of these details about the preparation of the building and the opening of the hospital are here given for the purpose of showing how inexpensively and easily an old building can be

p. 6

transformed into a fairly good modern hospital in a short time, and how easy it is in any community to make provision for the treatment of the consumptive poor without waiting until a great deal of money is at hand and ideal conditions present themselves. It, moreover, will be of importance to keep all of these matters in mind in connection with the results.

The wards of the hospital were opened on April 20th. It had taken all of this time to put the house in condition for the reception of patients. Meanwhile the dispensary service had grown very large. When the wards were opened they filled very rapidly -more rapidly, indeed, than was desirable, for it was difficult to secure a nursing staff. The fear of tuberculosis materially interfered with the organization of a nursing staff. The nursing problem was finally solved by opening a training school with girls who had been cured at the White Haven Sanatorium. The Institute is thus doing a double good work, that of training women for the care of consumptives and that of making an occupation for cured consumptives. The nursing staff at the end of the first year consisted of five trained nurses and five pupil nurses.

As the work increased in the dispensary the medical staff was augmented, and by the time the wards were open quite a fairsized staff had been organized. As with the nursing staff, there was some difficulty in organizing a medical staff, partly on account of fear of tuberculosis and partly, perhaps in a greater degree, on account of the high grade of men needed. Inasmuch as the Institute is for the study of tuberculosis as well as for its treatment and prevention, men not only of ability, but with preliminary training for original research and advancement of medical science had to be selected. At the end of the first year there were sixteen men on the medical staff.

The work accomplished by the Institute during the first year is interesting for its magnitude as well as for its scientific and philanthropic worth. Its magnitude in some measure detracts from its scientific value, because during the period of organiza-

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tion pressure of work led to inaccuracies of observation and incompleteness of records. Besides, men had to be trained for the work, as it was along new lines. To do exact scientific work in a dispensary was a new departure. It had to be made clear, moreover, that the Institute stood for science as well as for charity. An earnest effort was made by all to do good work, and whatever shortcomings occurred grew out of inexperience and overwork. The magnitude of this first year's work is in a measure indicated by the records of cases, which in bound form consist of ten octavo volumes of about one thousand pages each. These records are brimful of scientific data, and will form the basis of future scientific papers. Some of the data are summarized in this report.

It has taken much labor of the most painstaking kind to put this first year's records into exact order, because of the confusion which grew out of the excessive amount of work always on hand during the year. From the beginning each patient as he applied for treatment was given a number in consecutive order and his name was inscribed on a history sheet for examination. At all times there were more patients in the dispensary than could be taken care of by the medical and clerical staffs. Sometimes patients were given numbers, but could not be reached by the physician, and sometimes the physician in the desire to help as many of these poor people as possible allowed sympathy to get the better of science, and gave treatment without a complete record. It takes an hour to make a complete scientific record of a patient, and with a crush in the waiting-room men gave treatment without a history in the expectation of getting leisure to take the history later on when the pressure was less, but such a time never came and the history was not taken. This sympathetic interference with the scientific work of the Institute finally was checked by creating a waiting list in the dispensary and assigning new cases to men only as they could take care of them.

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Some confusion also grew out of mistakes of the clerical staff. In a few instances the same number was given to two patients, and in a few others two numbers were given to the same patient returning for treatment unrecognized as having been there before.

The records have been put in perfect order and all mistakes have been carefully eliminated. Future mistakes are guarded against by our present system of records. All patients now are entered numerically in a book and indexed alphabetically in a card index. Besides, the history sheets are filed away in numerical order in sections of ten.

The highest numbered history sheet at the end of the year was twenty hundred and forty-eight. A careful elimination of all errors shows that twenty hundred and thirty-nine patients were treated. Eight patients had received two histories each, two patients had received the same number, and two numbers had been skipped.

Of the patients treated, two hundred and fifty-four were treated in the hospital. Of these, one hundred and eighteen were treated in the dispensary before admission into the hospital or after discharge. The number of patients who received treatment in the dispensary therefore was nineteen hundred and three.

Nine hundred and four dispensary patients made one visit only; some because they entered the hospital; some because they were unsuitable; some because they did not have tuberculosis; and others because they merely came for an opinion.

Of the persons registered for treatment, three hundred and sixty did not have tuberculosis, two hundred and fourteen were unsuitable in that they could afford to pay for their treatment, and seven had no diagnosis recorded. In all, therefore, fourteen hundred and fifty-eight poor people with tuberculosis applied for treatment.

In the dispensary nine hundred and ninety-nine patients made more than one visit. These made a total of six thousand eight hundred and seventy-six visits, or an average of six and eighttenths visits each. The entire number of visits made in the dispensary was seven thousand seven hundred and eighty-one.

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Of the patients admitted into the hospital, two hundred and forty-five had tuberculosis; seven had no diagnosis recorded; one was recorded as having bronchitis, and one was undiagnosed. One patient who had been diagnosed as having tuberculosis was found on autopsy also to have had bronchiectasis. This patient is made the subject of a special report. The patient who was recorded as having bronchitis remained in the hospital only twelve days. This diagnosis was not scientifically established. The probabilities are that the patient had tuberculosis. One of the seven patients of whom no diagnosis was recorded, was diagnosed as having tuberculosis at autopsy. She died one-half hour after admission. The other six left the hospital before a diagnosis could be made. The two hundred and fifty-four patients spent twelve thousand and sixty-eight days in the hospital, averaging forty-eight and seven hundredths days each. Forty patients were in the hospital less than one week. Of these, ten died and the others left for various reasons. The longest stay of any patient was two hundred and eighty-six days. This patient was in the hospital at the end of the year. He was a most advanced case when he came in, but had steadily improved.

NATIVITY

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NATIVITY.—(Continued)

MIXE PARENTAGE

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MIXED PARENTAGE.—(Continued.)

Nearly one-half of all patients registered were foreign-born. The foreign-born males exceeded the foreign-born females about 19 %. Many of the foreign-born have been in the country so short a time that it may be assumed they had the disease when they landed on our shores.

It is interesting to note the places from which the foreign-born patients came. Russia supplied us the greatest number in the first generation, Ireland the next greatest number, and Germany the next. Going one generation back, Ireland changes places with Russia. In a measure the number of cases from the various countries is in ratio with the immigration from those countries. Russia is sending us the largest number of immigrants in the immediate generation and Ireland sent us the largest number in the past generation. The racial element in these statistics unfortunately is incomplete. It would have been interesting to have singled out the Jews with a view of throwing light upon the question of immunity. In future this will be done. The majority of the patients from Russia, Roumania, Austro-Hungary, and Poland, however, were Jews. 2 Racial science is prominent in this kind of discussion. Explicitly, they are talking about Jewish people

Age

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More than one-half of the patients registered for treatment were of the age which is of the greatest importance to the public weal. During the age-period between twenty and forty, men and women not only are of greatest value as producers of wealth, but are important factors in the propagation of the species. Death during this life-period is a serious blow to the public weal. It not only strikes at the source of wealth, but also puts a drag on the public weal in the production of dependent orphans. Most people who die between twenty and forty leave behind them dependent children, and inasmuch as tuberculosis is a longdrawn-out disease, dependent children who have been made orphans by this disease are apt to become public charges.

SEX. Male,1179 Female,851 No Record,9

The number of males greatly exceeds the number of females. This is probably due in part to the foreign element. This preponderance cannot be accepted as an index of respective liability of the sexes to tuberculosis.

COLOR.

The vast preponderance of white people over colored people among the patients registered is no indication of the relative amount of tuberculosis in the races, nor of their relative poverty. The colored people are much more prone to tuberculosis than are the white people. There probably is as much poverty among the colored people as among the whites. The colored people, however, are more loath to become a public charge and are more disposed to help themselves. They will not go into a public institution if they can manage to crawl around. The proportion of colored admissions to white admissions, however, was

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greater than is the proportion of the colored population to the white population in Philadelphia. The number of colored admissions was about 6 1/2% of the white admissions.

RESIDENCE

As will be seen from the table, vastly the majority of the patients were from Philadelphia. A reference to the map published as a part of this report, which gives the location of patients in the city of Philadelphia, will show that the majority of the patients came from the immediate vicinity of the Institute. The Institute is located in the poorest district of Philadelphia, and quite naturally a great deal of tuberculosis exists in this district. This map, however, cannot be accepted as an indication of the prevalence of tuberculosis in Philadelphia. The probabilities are that the disease is fully as prevalent in the mill districts of the city.

SOCIAL CONDITION

There are two elements in the statistics of the social condition of the patients worthy of notice: one the number of married people, and the other the number of widowed. Forty per cent. of the patients who applied for assistance were married and consequently destined, unless the disease could be arrested, to leave orphaned children and widowed consorts. Inasmuch as the poverty of these poor people is distressing, it is to be anticipated that unless restored to health they will almost necessarily become a public charge. It is remarkable that nearly nine per cent. of the applicants were already widowed. What a sad picture of distress and sorrow can be conjured up out of these figures!

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OCCUPATION

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OCCUPATION.-(Continued.)

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OCCUPATION.-(Continued.)

In the occupations of those who applied for treatment some very interesting points present themselves. For a correct interpretation of occupation statistics one needs to keep in mind such factors as the remuneration which goes with the occupation, the severity of the labor involved, the propensities to alcoholism, the presence of irritating substances in the air of places of employment, and the relative number of people employed in the occupation. The occupation from which the highest number came for treatment at the Phipps Institute during the year is housework. In this connection it must be borne in mind that among the poor all married women and most widows give their occupation as housework. The wife and mother is most intensely

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exposed to contagion in a household in which there is tuberculosis. It is not a matter for surprise, then, that of the women who apply for charity in the treatment of tuberculosis nearly one-half are houseworkers. The number of women who applied for treatment is eight hundred and fifty-one and the number of houseworkers is three hundred and sixty. The other female occupations most numerously represented in the table are, in respective order: factory hand, forty-seven; weaver, thirty-two; seamstress, thirty-three; laundry-worker, fourteen; store employee, twelve; and nurse, seven. Some of these occupations are pursued by men as well as women. The occupation of seamstress is the only one exclusively filled by women. With this occupation the question of remuneration plays a part. Seamstresses are poorly paid and are compelled to work in unhygienic environments.

The male occupation which stands at the head of the list is that of laborer, with one hundred and one. The laborer is not only poorly paid, and consequently poorly fed, but lives in poor environments. He has more chance of having the disease in his home than most people, by reason of his poverty, and consequently he is more apt to be exposed to contagion than most people. A group of occupations all belonging to the same category is that of tailor with fifty-nine; that of clerk with forty-three; that of cigarmaker with thirty; that of salesman with thirteen; that of printer with fourteen; and that of shoemaker with twelve. In all of these occupations there is poor pay, which means deprivation at home, and bad sanitary conditions in the place of occupation. Another group is that in which alcohol plays a part; those occupations in which, by reason of association, exposure, or hard work, there is a temptation to use alcohol in some form or other. To this group belongs the occupation of driver with forty-two; that of waiter with twenty-one; bartender with fourteen; plumber with ten; and cook with ten. In these occupations neither want of food nor lack of fresh air plays a part. There is usually plenty to eat and there is either outdoor life or fair indoor

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environment. The propensity to tuberculosis in these cases is due to alcoholism. In these occupations the temptation and opportunity for the use of alcohol are great. Another group is that in which occupation exposes to inhalation of irritating substances given off in manufacturing processes. These irritating substances may act in two ways, one as a medium of contagion, the other as a means of traumatism. They probably act in both ways. To this group belongs the occupation of mill-hand with sixty-four; machinist with thirty-five; weaver with thirty-two; iron-worker with twenty-one; upholsterer with nine; and leatherworker with nine. The high morbidity in some of the occupations is only intelligible upon the assumption that the occupations were taken up after the disease had been contracted, because the occupations are easy and out-of-doors. Such are, for example, the occupations of canvasser, agent, collector, and peddler. The occupation of car conductor, I know, is frequently taken up by persons who have had tuberculosis and who have made a partial recovery.

ALCOHOLISM

In former times alcohol was looked upon as a preventive and cure of tuberculosis. At the present day alcohol is looked upon as a predisposing cause of the disease and as an impediment to recovery. Neither of these views apparently gets much support from the statistics here given. The word “alcoholism" as here used means an excessive use of alcohol, but not necessarily a use of alcohol to the degree of drunkenness. A person was not put down as an alcoholic unless he used enough alcohol to do himself some physical harm. Of course, it is not easy to get a history of alcoholism from a patient, and some allowance must be made on this score for the smallness of the numbers. As the figures stand, however, the percentage of alcoholics among consumptives and among the relatives of consumptives does not

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seem to differ very much from that of nonconsumptives and relatives of nonconsumptives.

PREDISPOSING DISEASES.

It has been held that certain diseases greatly predispose to tuberculosis. This view has originated from the observation that these diseases frequently precede tuberculosis within a few years, and sometimes within a few months. The diseases which have best earned this reputation are typhoid fever, pneumonia, and pleurisy. The figures would seem to indicate that pleurisy most frequently precedes tuberculosis, pneumonia next, and typhoid fever last. More than one-half the cases were preceded by one or the other of these diseases. There is good reason to believe that the pleurisies, pneumonias, and typhoid fevers which precede tuberculosis frequently are tuberculosis which goes unrecognized and simulates the diseases named. Some observers even claim that practically all pleurisies are tuberculous. That irregular forms of pneumonia and typhoid fever often are tuberculosis cannot be doubted.

SOURCE OF CONTAGION.

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An earnest effort has been made in history-taking to discover the source of contagion of each case. In the majority of cases this was made out to the extent, at least, of finding a known source of contagion. In many cases, however, owing to the ignorance and prejudice of patients and their inability to understand and speak the English language, it was impossible to get a satisfactory history. The histories of exposure to contagion which could be gotten emphasize in a striking manner the part which family relationship plays in the spread of tuberculosis. With this picture before one, it is easy to understand why the ancients looked upon tuberculosis as an inherited disease. More than two-thirds of the cases in which a history of exposure to contagion could be obtained gave contagion from blood relatives as the source of the disease. The number of cases in which the disease was derived from consorts or from members of their families is surprisingly large, and the number of cases which gave fellowemployees and infected houses as the source of contagion is surprisingly small. Of course, it must not be lost sight of that family contagion is always the most evident and easily recognized and that the large number of cases in which the source of contagion remained undiscovered were in all probability cases of occupation and house contagion. These forms of contagion are sometimes difficult to ferret out even with intelligent observing people, because one cannot always know when he is working with a consumptive or when the home into which he moves has been occupied by a consumptive. Some of the patients gave histories of double and even triple exposure.

PLACE OF BEGINNING OF TUBERCULOSIS OF THE LUNGS.

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An effort has been made to determine in what part of the lungs the disease began. The conclusions here recorded were reached by trying to determine on which side the disease had made the greatest ravages. The side which had the most extensive lesion was recorded as the side on which the disease began. This cannot always be accepted as a safe deduction. Neither can it be said that the observations upon which these records are based are entirely reliable. The records, however, strongly support the universally accepted view that the right lung is most frequently the first affected.

TISSUE INVOLVED.

A fair picture of the stages of tuberculosis in which patients applied for treatment is presented in this table. The picture is underdrawn rather than overdrawn. In the beginning of the service incomplete records were made. Of the dispensary patients more than one-half had both lungs involved and about onethird were far advanced in the disease. Of the hospital patients only a little over 7 % had the disease limited to one lung. All this shows how slow people with tuberculosis are to recognize that they are ill and need medical attendance. Tuberculosis is such an insidious disease that it makes great progress before its existence is even suspected by the victim.

FREEDOM FROM COUGH.

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It is usually taken for granted that cough is an essential symptom of pulmonary tuberculosis. Cough is a usual symptom, but not an essential one. It may be absent in tuberculous patients and it may be present in nontuberculous patients. Forty-one patients who were diagnosed as having tuberculosis were free from cough. At rest, with proper regulation of diet, tuberculous patients cough very little. In the hospital no cough medicines are used, and although the patients all are advanced, many with both lungs extensively diseased, there is very little coughing.

TUBERCLE BACILLI IN SPUTUM.

Many sputum examinations were not recorded. This was on account of the constant pressure of work. Of the cases recorded, a little less than two-thirds showed the presence of tubercle bacilli in a limited number of examinations. This gives a fair picture of the frequency with which sputum of tuberculous patients is negative. One or two examinations, when negative, mean very little. Tubercle bacilli may be absent from the sputum upon repeated examinations even in advanced cases. This was demonstrated in some of the cases which came to autopsy. A negative report on sputum, even when repeated examinations have been made, should not be allowed to stand against positive clinical evidence of tuberculosis in making a diagnosis. It is only when the clinical symptoms agree with the negative report of the sputum that a negative diagnosis should be made.

HOARSENESS.

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Hoarseness in tuberculosis is not necessarily an indication of laryngeal tuberculosis even when the hoarseness is persistent. Usually persistent hoarseness does mean laryngeal tuberculosis. Tuberculosis of the pharynx and tonsils occurs pretty often in advanced stages of the disease and sometimes accounts for persistent hoarseness. Mixed infection alone may be responsible for this symptom, however. Chronic catarrhal rhinitis and pharyngitis occur frequently in tuberculosis and sometimes keep up hoarseness for a long time.

DISEASES OF THE CIRCULATORY SYSTEM. These statistics upon lesions and functional diseases of the circulatory system, it must be admitted, cannot be accepted as giving an accurate picture of the frequency with which such conditions occur in tuberculosis. It requires great skill and large clinical experience to make exact trustworthy records of organic heart lesions. Such skill and experience cannot be claimed for the medical staff in the beginning of the work, at least. In many cases, moreover, no record was made at all of the condition of the circulatory system. Even in the matter of functional disturb-

p. 24

ances, such as accentuated second sound, the record is very incomplete. Some of the members of the staff recorded accentuated second sound in a majority of the patients and others recorded it in almost none. Neither was there always a distinction made between accentuation of the aortic second sound and the accentuation of the pulmonic second sound. This kind of work is more accurately done now than it was in the beginning, so that future statistics will throw more light upon the subject.

URINARY ABNORMALITIES.

Although it is part of the program of the Institute to make a careful urinary analysis of all patients who apply for treatment, little was accomplished in this line during the first year. Many examinations which were made were not recorded, and there is no way of determining the number of cases on which this table is based. Our shortcomings were due principally to the heavy pressure under which we have worked from the beginning and to the lack of facilities for such work.

GENITO-URINARY DISEASE.

The statistics here given, it must be frankly admitted, are unreliable. In many cases the thorough investigation necessary for determining whether or not there was genito-urinary involvement was not made. It is not an easy matter to determine clinically whether or not such organs are tuberculous. The symptoms which may indicate genito-urinary tuberculosis may also

p. 25

indicate other diseases, and it is sometimes impossible to differentiate. Besides, in the cases in which genito-urinary disease is recorded there is no record as to whether or not the genito-urinary diseases were tuberculous in character.

HEMOPTYSIS.

It is rather surprising that so large a percentage of cases gave a history of hemoptysis. This same ratio probably would not hold with people better situated in life. Hemoptysis undoubtedly is largely due to overexertion. The pulmonary circulation becomes embarrassed by reason of obstruction and the heart is stimulated to greater effort. Bodily fatigue adds to this overaction, and with contraction of the blood-vessels hemorrhage The patients who entered the hospital and were placed at rest remained almost free from hemorrhages even in the advanced stages.

NIGHT-SWEATS.

In practically all of the patients in the hospital the nightsweats stopped after the patient had been at rest for awhile and had had his diet regulated. No drugs are used in the hospital for night-sweats and none are necessary. The large number of cases with night-sweats both in the hospital and dispensary indicates how advanced many of the patients were when they came under treatment. It also shows how few patients with tuberculosis come under treatment early.

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DIARRHEA.

Of the patients with persistent diarrhea, fifty were in the hospital. Persistent diarrhea in a tuberculous patient usually indicates that the patient has tuberculous ulceration of the bowels. Sometimes, however, extensive ulceration of the bowels exists without much disturbance of the bowels; and sometimes great disturbance of the bowels exists without ulceration.

EDEMA.

Edema in tuberculosis usually is the result of damaged circulation following in the wake of the tuberculous process in the lungs and other organs. Right-sided dilatation of heart with consequent dilatation of the left heart occurs frequently in advanced tuberculosis. This no doubt plays a part in edema. Tuberculosis of the kidneys, however, probably also plays a part. The kidneys frequently become the seat of tuberculosis. The records as given here probably understate the percentage of cases in which edema occurs in tuberculosis. In many cases no careful investigation was made for edema and no records were kept.

DURATION OF DISEASE.

The records here given understate the actual duration of the disease. It takes considerable experience to be able to bring

p. 27

out the full duration of tuberculosis when taking the history of a case. In our first year's work there has been a continuous increase in the duration of disease as the experience of our men grew in taking histories. Patients, as a rule, fix the beginning of the disease by the first severe break in health. As a matter of fact, the beginning of tuberculosis gives no symptoms. Very often even a number of serious interferences with health, recurring at intervals of three to six months, may take place before suspicion points to what is the matter. Tuberculosis exists from the time of implantation, and the duration of the disease really should be counted from the time of exposure to contagion.

WEIGHT.

The weights given in this table are net weights. When a patient gained and then lost, only that which he held was counted; and when a patient lost and then gained, only the gain above

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what he weighed when he began treatment was counted. In the same way the losses were based upon the weight when treatment began.

Weight is a criterion of the progress of tuberculosis up and down. Loss of weight undoubtedly is one of the results of tuberculous toxemia. One of the first evidences of deterioration is loss of weight. An early sign of improvement in a tuberculous patient, on the other hand, is gain in weight. While this is the rule, there are exceptions. Tuberculosis may terminate fatally without emaciation. A person with tuberculosis may be so fed up as to become quite rounded and well filled out and still go on to death. In these cases death is usually due to complications of one kind or another. Sometimes so many organs have been damaged by the tuberculous process that life is snuffed out by a simple cold. This is especially true when the kidneys are extensively diseased.

Both in the dispensary and in the hospital there were some very large gains. Along with these gains went general improvement and progress toward recovery. The highest gain in the hospital was thirty-three and one-half pounds. The greatest loss in the hospital was twenty-five and three-quarter pounds. The highest gain in the dispensary was thirty-nine pounds and the greatest loss in the dispensary was thirty and one-quarter pounds.

RESULTS OF TREATMENT.

The word improved is here used to indicate any amelioration of symptoms with increase in weight and gain in physical health--

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one or both. The improvement in some cases was very marked, and this applies even to advanced cases. Some of the patients who came into the hospital as advanced cases were restored to a condition of physical health which enabled them to return to their occupations. Unimproved includes all cases in which there was no perceptible progress toward recovery. Even patients who gained weight for awhile and lost it again, were recorded as unimproved. The cases recorded as unimproved sometimes were lost sight of, either by removal from the hospital or by giving up treatment at the dispensary. Many of them no doubt died. The record of deaths in the dispensary, and in a less degree in the hospital, for this reason, has little value.

SPECIAL WORK.

For the purpose of studying tuberculosis from every possible point of view and giving relief in all forms of the disease, special departments have been established in the Institute and others will be established as the work develops. Up to the present time there have been organized a neurological staff, a laryngological staff, and a dermatological staff. The laboratory, both in its bacteriological department and in its pathological department, has been established and partly equipped, but not fully organized. A consulting ophthalmologist has been appointed on the staff. Separate reports on laryngological and neurological work are made by Drs. Geo. B. Wood and D. J. McCarthy. Dr. Joseph Walsh reports upon the autopsies and Dr. M. P. Ravenel upon a case of fibroid phthisis. Drs. H. R. M. Landis and J. W. Irwin report special work assigned by the medical director.

PREVENTION OF TUBERCULOSIS.

One of the objects of the Institute is the prevention of tuberculosis. What has been accomplished during the year in this direction cannot be recorded, because it cannot be measured. The patients who have been taken into the hospital have been taken out of squalid, poverty-stricken homes, where they had

p. 30

been sources of danger to others. The probabilities are that every removal of such a patient has been the means of preventing at least one implantation. Even when the patient returned again to his home, something had been accomplished, because he went home trained in preventive measures. All the dispensary patients are taught and drilled in preventive measures. As each patient comes into the waiting-room he is handed a spit-cup, and during his stay is taught to use it. When he goes away he is given a tin spit-cup holder, a bundle of paper cups, and a bundle of paper napkins and paper bags to take home with him. He is also given a set of rules on a large cardboard to hang up in his house, and on a folder to carry in his pocket. Every time he comes back to the dispensary he is given a new supply of preventive measure material, and is further instructed in its use. At regular intervals he is visited in his home by a pupil nurse and is given such instruction and assistance as he may need for prevention of the spread of the disease.

FOOD.

In the hospital all patients are placed upon a carefully selected diet. This consists of milk, eggs, and plain nutritious food. As a rule, patients take three quarts of milk and six raw eggs a day and one meal of solid food. This meal consists of beef or mutton, fresh vegetables, and fruit. To the dispensary patients milk is served at their homes from the Institute wagon or through milkmen. In the beginning all milk was served through milkmen. This system of serving through milkmen was not found satisfactory, first because the Institute could not control the quality of the milk, and secondly because the system was open to fraud. As an experiment the Institute has equipped a milk wagon of its own.

MEDICINE.

To the house patients all medicine is furnished free. To the dispensary patients it is furnished either free or at a nominal

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cost. A nominal charge, consisting of twenty-five cents for one prescription, forty cents for two prescriptions, and fifty cents for three or more prescriptions to one and the same person at the same time, is made to such patients as can afford it, for two reasons: first, to give them a semblance of independence; and, secondly, to discourage as far as possible unnecessary drugtaking. The majority of dispensary patients are, however, unable to maintain even this little pretense of self-support.

SCIENTIFIC RESEARCH.

The study of tuberculosis is one of the purposes of the Institute. For this reason a laboratory and pathological museum and an autopsy room have been equipped. In the crowded, cramped quarters of the Institute in its temporary home, it has been difficult to carry out this purpose. Something has been accomplished, however. Nearly all patients who have died have been carefully autopsied; a valuable collection of pathological specimens has been collected; many sections have been made for microscopic study, and a beginning has been made in laboratory research. The staff meets weekly for scientific discussion and exchange of thought. All work done is carefully scrutinized and criticized at these meetings.

EDUCATIONAL WORK.

Early in the Institute's first year an international lecture course on tuberculosis was got up for the education of the public. Prominent workers from different parts of the world were brought to Philadelphia to speak to the world from a Philadelphia platform. The lectures delivered on these occasions were published in the medical journals and in abstract in the daily papers. They are republished as part of this first annual report, although all of them were not delivered within the first year.

The lecturers were Drs. E. L. Trudeau, of Saranac; Wm. Osler, of Baltimore; G. Sims Woodhead, of Cambridge, England;

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Herman M. Biggs, of New York; and Edoardo Maragliano, of Italy. Dr. Trudeau, the pioneer worker in the field of tuberculosis in America, opened the course. He was followed by the other gentlemen in the order named. Dr. Maragliano was prevented from coming to America at the last moment by serious personal illness, but his paper was read at the time set for his appearance and was subsequently published. The course of lectures was well attended and the publication of the lectures has stimulated much activity in the warfare against the disease. On the occasion of Dr. Maragliano's lecture the National Association for the Study and Prevention of Tuberculosis was organized.

THE FIRST YEAR'S HARVEST.

To organize a new work is a difficult undertaking. The Henry Phipps Institute for the Study, Treatment, and Prevention of Tuberculosis is in its conception and establishment an embodiment of a new idea-namely, concentrated effort upon a single disease for its extermination. The financial resources were at hand through the generosity of Mr. Henry Phipps, but there was no precedent for the creation of machinery and the formation of the line of battle. Everything had to be worked out and tested. Classical prejudices of all kinds and complexions stood in the way. The line of action lay in opposition to preconceived notions and the teaching of medicine for generations. Weighed in the balance of these difficulties, the harvest of the first year's labor has been good. In addition to what has been accomplished in treatment, prevention, and education, there has been some golden fruit in the training of medical experts and special nurses. This perhaps is the best of the Institute's work. The training of women for the care of tuberculous subjects and the creation of a new field of labor for women who have had tuberculosis and have recovered, perhaps, would be worth the labor and money which have been expended. These women become missionaries in the crusade against tuberculosis.

LAWRENCE F. FLICK.

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First Annual Report of the Henry Phipps Institute for the Study, Treatment, and Prevention of Tuberculosis

Published by the Henry Phipps Institute. 238 Pine Street. Philadelphia. 1905.

irst Annual Report of the Henry Phipps Institute for the Study, Treatment, and Prevention of Tuberculosis Henry Phipps Institute 1905
This refers to any moment a patient is being referred to within the text. This refers to any moment a patient's biometrics, symptoms, or individual life is described. Anything that could be drawn to identify this subject is included. Mention of an autopsy performed Whenever a case study is mentioned. Information about scientific practices, usually related to actions employed during research. Description of multiple cases at once, or talking in the aggregate about the progression of the disease. When a doctor prescribes or does something to cure the patient. A table found in the information. (This has been formatted from the original OCR'd text.) background-color: #cccccc; font-color: #666666; Drug Store On site drug store (can say more about them) Laboratories On site laboratories (can say more about them) Diet Kitchens Describe why a diet kitchen on site is important.
Commentary on racial science. FIRST ANNUAL REPORT OF THE HENRY PHIPPS INSTITUTE FOR THE STUDY, TREATMENT, AND PREVENTION OF TUBERCULOSIS A BRIEF ACCOUNT OF THE WORK OF THE FIRST YEAR AND A REPRINT OF THE LECTURES DELIVERED UNDER THE AUSPICES OF THE INSTITUTE DURING THE YEAR PUBLISHED BY THE HENRY PHIPPS INSTITUTE 238 PINES STREET, PHILADELPHIA TEMPORARY QUARTERS, 238 PINE STREET. THE WORK OF THE FIRST YEAR

The Henry Phipps Institute was founded on February 1, 1903. It was incorporated September 1, 1903. The purposes of the Institute as set forth in its charter are: “The study of the cause, treatment, and prevention of tuberculosis, and the dissemination of knowledge on these subjects; the treatment and the cure of consumptives. The benefits shall be administered without regard to race, creed, or color.” The founder of the Institute is Henry Phipps, Esq., who also maintains it. Incorporators are Henry Phipps, Esq., Lawrence F. Flick, M.D., Mr. Geo. E. Gordon, Miss Amy F. Phipps, and Mr. Samuel Harbison.

Clinical work was begun in the Phipps Institute in temporary quarters at 238 Pine street, Philadelphia, on the second day of February, 1903, the day after foundation. Dispensary patients were seen on that day and from that day on. From the first day on which work was begun the number of patients exceeded the capacity of the Institute for clinical work. Bare floors and walls of the first-story front room, a few chairs, a clerk, and three physicians constituted the equipment at the start. Dispensary work and fitting up went hand in hand for months. During this time order was brought out of chaos and the lines of work were developed, until finally a complete organization was brought into existence. In the beginning arrangements were made with a drug-store to supply medicine and with milkmen to supply milk to patients to whom these articles had to be given free. These were temporary makeshifts until the Institute could create its own machinery for supplying these commodities.

Number 238 Pine street is a well-built, large structure, which

had been put up for lodge purposes but had been unoccupied for some years. It is a four-story building with a small threestory back building. The back building evidently was an old house which had been moved back. The front building is twentysix feet front and sixty-six feet deep and the back building is eighteen by thirty-two feet in dimensions. There is a side yard and å back yard, the side yard being a narrow strip seven and onehalf by thirty-two feet and the back yard an area of twenty-five by thirty-three feet. The front building has high ceilings on each floor with fine large windows on two sides on the first floor, and three sides on the second, third, and fourth floors. On the first floor there is a hallway with a stairway in the rear and two large rooms which, no doubt, were used as reception rooms or parlors. On the second, third, and fourth floors of the front building there is, on each, one large room, two small rooms, and a stairway landing. In the back building on the first floor there is a very small kitchen, a very small dining room, and a back stairway leading to the second floor. On the second floor there is one small bedroom and a bathroom with a stairway leading to the third floor. On the third floor there is one small bedroom. In the back building all the ceilings are low.

We divided the front room of the first floor into consultation rooms and an office, and the back room into a consultation room, a waiting-room, a drug-store, and a laboratory. We fitted up the little dining-room in the back building as a consultation room, and the little kitchen as an autopsy room. We made wards of the large rooms front on the second, third, and fourth floors, and a bathroom and linen room of one of the little rooms back on each floor. The other little room on each of the second and third floors we fitted up as a diet kitchen and that on the fourth floor as the kitchen proper. There were platforms on both sides in the front and the rear of the three large rooms front. We removed the platforms in the front and the rear and retained those on the sides. These were about six inches above the level of the floor.

We placed eighteen beds in each room on the second and third floors and sixteen in the room on the fourth floor. We put a dining table in each of the wards for the patients who are up and about and a food carriage to keep the food warm while being served. These three large rooms made excellent wards, having high windows on two sides, and a ventilator above a door on the third side. We placed three electric fans in each ward to supplement the natural ventilation and also to keep the wards cool in summer. We placed a gas range in the little kitchen on the fourth floor. This we did as a matter of cleanliness and economy.

The second floor of the back building we fitted up as a dining-room for the nurses. We lodged the nurses temporarily in rented rooms outside. A little corner of the room we fitted up as an office for the head nurse. The room on the third floor of the back building we fitted up as a sterilizing room and laundry. Opening out from this, we constructed a flat over the bathroom below for the purpose of drying clothing, and from this flat we ran lines to a pole at the end of the yard as a means of extending the facilities for drying clothes.

We put steam heat in the building, an electric pump for pumping water to the roof, and new plumbing. The back yard and cellar we cemented. We put up canopies in the back yard for the protection of patients while sitting out. We transformed the rear cellar into a pathological museum and part of the front cellar into a storage room. They immediately made a museum as part of the institute For sanitary reasons we had all the walls of the building scrubbed and repainted, all the woodwork thoroughly scrubbed, and the cellar walls whitewashed. We put electric lights in the cellar, on the fire-escape, and in the autopsy room, as a matter of safety against fire and also as a matter of convenience. For lighting the rest of the building we use gas.

All of these details about the preparation of the building and the opening of the hospital are here given for the purpose of showing how inexpensively and easily an old building can be

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transformed into a fairly good modern hospital in a short time, and how easy it is in any community to make provision for the treatment of the consumptive poor without waiting until a great deal of money is at hand and ideal conditions present themselves. It, moreover, will be of importance to keep all of these matters in mind in connection with the results.

The wards of the hospital were opened on April 20th. It had taken all of this time to put the house in condition for the reception of patients. Meanwhile the dispensary service had grown very large. When the wards were opened they filled very rapidly -more rapidly, indeed, than was desirable, for it was difficult to secure a nursing staff. The fear of tuberculosis materially interfered with the organization of a nursing staff. The nursing problem was finally solved by opening a training school with girls who had been cured at the White Haven Sanatorium. The Institute is thus doing a double good work, that of training women for the care of consumptives and that of making an occupation for cured consumptives. The nursing staff at the end of the first year consisted of five trained nurses and five pupil nurses.

As the work increased in the dispensary the medical staff was augmented, and by the time the wards were open quite a fairsized staff had been organized. As with the nursing staff, there was some difficulty in organizing a medical staff, partly on account of fear of tuberculosis and partly, perhaps in a greater degree, on account of the high grade of men needed. Inasmuch as the Institute is for the study of tuberculosis as well as for its treatment and prevention, men not only of ability, but with preliminary training for original research and advancement of medical science had to be selected. At the end of the first year there were sixteen men on the medical staff.

The work accomplished by the Institute during the first year is interesting for its magnitude as well as for its scientific and philanthropic worth. Its magnitude in some measure detracts from its scientific value, because during the period of organiza-

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tion pressure of work led to inaccuracies of observation and incompleteness of records. Besides, men had to be trained for the work, as it was along new lines. To do exact scientific work in a dispensary was a new departure. It had to be made clear, moreover, that the Institute stood for science as well as for charity. An earnest effort was made by all to do good work, and whatever shortcomings occurred grew out of inexperience and overwork. The magnitude of this first year's work is in a measure indicated by the records of cases, which in bound form consist of ten octavo volumes of about one thousand pages each. These records are brimful of scientific data, and will form the basis of future scientific papers. Some of the data are summarized in this report.

It has taken much labor of the most painstaking kind to put this first year's records into exact order, because of the confusion which grew out of the excessive amount of work always on hand during the year. From the beginning each patient as he applied for treatment was given a number in consecutive order and his name was inscribed on a history sheet for examination. At all times there were more patients in the dispensary than could be taken care of by the medical and clerical staffs. Sometimes patients were given numbers, but could not be reached by the physician, and sometimes the physician in the desire to help as many of these poor people as possible allowed sympathy to get the better of science, and gave treatment without a complete record. It takes an hour to make a complete scientific record of a patient, and with a crush in the waiting-room men gave treatment without a history in the expectation of getting leisure to take the history later on when the pressure was less, but such a time never came and the history was not taken. This sympathetic interference with the scientific work of the Institute finally was checked by creating a waiting list in the dispensary and assigning new cases to men only as they could take care of them.

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Some confusion also grew out of mistakes of the clerical staff. In a few instances the same number was given to two patients, and in a few others two numbers were given to the same patient returning for treatment unrecognized as having been there before.

The records have been put in perfect order and all mistakes have been carefully eliminated. Future mistakes are guarded against by our present system of records. All patients now are entered numerically in a book and indexed alphabetically in a card index. Besides, the history sheets are filed away in numerical order in sections of ten.

The highest numbered history sheet at the end of the year was twenty hundred and forty-eight. A careful elimination of all errors shows that twenty hundred and thirty-nine patients were treated. Eight patients had received two histories each, two patients had received the same number, and two numbers had been skipped.

Of the patients treated, two hundred and fifty-four were treated in the hospital. Of these, one hundred and eighteen were treated in the dispensary before admission into the hospital or after discharge. The number of patients who received treatment in the dispensary therefore was nineteen hundred and three.

Nine hundred and four dispensary patients made one visit only; some because they entered the hospital; some because they were unsuitable; some because they did not have tuberculosis; and others because they merely came for an opinion.

Of the persons registered for treatment, three hundred and sixty did not have tuberculosis, two hundred and fourteen were unsuitable in that they could afford to pay for their treatment, and seven had no diagnosis recorded. In all, therefore, fourteen hundred and fifty-eight poor people with tuberculosis applied for treatment.

In the dispensary nine hundred and ninety-nine patients made more than one visit. These made a total of six thousand eight hundred and seventy-six visits, or an average of six and eighttenths visits each. The entire number of visits made in the dispensary was seven thousand seven hundred and eighty-one.

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Of the patients admitted into the hospital, two hundred and forty-five had tuberculosis; seven had no diagnosis recorded; one was recorded as having bronchitis, and one was undiagnosed. One patient who had been diagnosed as having tuberculosis was found on autopsy also to have had bronchiectasis. This patient is made the subject of a special report. The patient who was recorded as having bronchitis remained in the hospital only twelve days. This diagnosis was not scientifically established. The probabilities are that the patient had tuberculosis. One of the seven patients of whom no diagnosis was recorded, was diagnosed as having tuberculosis at autopsy. She died one-half hour after admission. The other six left the hospital before a diagnosis could be made. The two hundred and fifty-four patients spent twelve thousand and sixty-eight days in the hospital, averaging forty-eight and seven hundredths days each. Forty patients were in the hospital less than one week. Of these, ten died and the others left for various reasons. The longest stay of any patient was two hundred and eighty-six days. This patient was in the hospital at the end of the year. He was a most advanced case when he came in, but had steadily improved.

NATIVITY

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NATIVITY.—(Continued)

MIXE PARENTAGE

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MIXED PARENTAGE.—(Continued.)

Nearly one-half of all patients registered were foreign-born. The foreign-born males exceeded the foreign-born females about 19 %. Many of the foreign-born have been in the country so short a time that it may be assumed they had the disease when they landed on our shores.

It is interesting to note the places from which the foreign-born patients came. Russia supplied us the greatest number in the first generation, Ireland the next greatest number, and Germany the next. Going one generation back, Ireland changes places with Russia. In a measure the number of cases from the various countries is in ratio with the immigration from those countries. Russia is sending us the largest number of immigrants in the immediate generation and Ireland sent us the largest number in the past generation. The racial element in these statistics unfortunately is incomplete. It would have been interesting to have singled out the Jews with a view of throwing light upon the question of immunity. In future this will be done. The majority of the patients from Russia, Roumania, Austro-Hungary, and Poland, however, were Jews. Racial science is prominent in this kind of discussion. Explicitly, they are talking about Jewish people

Age

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More than one-half of the patients registered for treatment were of the age which is of the greatest importance to the public weal. During the age-period between twenty and forty, men and women not only are of greatest value as producers of wealth, but are important factors in the propagation of the species. Death during this life-period is a serious blow to the public weal. It not only strikes at the source of wealth, but also puts a drag on the public weal in the production of dependent orphans. Most people who die between twenty and forty leave behind them dependent children, and inasmuch as tuberculosis is a longdrawn-out disease, dependent children who have been made orphans by this disease are apt to become public charges.

SEX. Male,1179 Female,851 No Record,9

The number of males greatly exceeds the number of females. This is probably due in part to the foreign element. This preponderance cannot be accepted as an index of respective liability of the sexes to tuberculosis.

COLOR.

The vast preponderance of white people over colored people among the patients registered is no indication of the relative amount of tuberculosis in the races, nor of their relative poverty. The colored people are much more prone to tuberculosis than are the white people. There probably is as much poverty among the colored people as among the whites. The colored people, however, are more loath to become a public charge and are more disposed to help themselves. They will not go into a public institution if they can manage to crawl around. The proportion of colored admissions to white admissions, however, was

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greater than is the proportion of the colored population to the white population in Philadelphia. The number of colored admissions was about 6 1/2% of the white admissions.

RESIDENCE

As will be seen from the table, vastly the majority of the patients were from Philadelphia. A reference to the map published as a part of this report, which gives the location of patients in the city of Philadelphia, will show that the majority of the patients came from the immediate vicinity of the Institute. The Institute is located in the poorest district of Philadelphia, and quite naturally a great deal of tuberculosis exists in this district. This map, however, cannot be accepted as an indication of the prevalence of tuberculosis in Philadelphia. The probabilities are that the disease is fully as prevalent in the mill districts of the city.

SOCIAL CONDITION

There are two elements in the statistics of the social condition of the patients worthy of notice: one the number of married people, and the other the number of widowed. Forty per cent. of the patients who applied for assistance were married and consequently destined, unless the disease could be arrested, to leave orphaned children and widowed consorts. Inasmuch as the poverty of these poor people is distressing, it is to be anticipated that unless restored to health they will almost necessarily become a public charge. It is remarkable that nearly nine per cent. of the applicants were already widowed. What a sad picture of distress and sorrow can be conjured up out of these figures!

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OCCUPATION

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OCCUPATION.-(Continued.)

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OCCUPATION.-(Continued.)

In the occupations of those who applied for treatment some very interesting points present themselves. For a correct interpretation of occupation statistics one needs to keep in mind such factors as the remuneration which goes with the occupation, the severity of the labor involved, the propensities to alcoholism, the presence of irritating substances in the air of places of employment, and the relative number of people employed in the occupation. The occupation from which the highest number came for treatment at the Phipps Institute during the year is housework. In this connection it must be borne in mind that among the poor all married women and most widows give their occupation as housework. The wife and mother is most intensely

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exposed to contagion in a household in which there is tuberculosis. It is not a matter for surprise, then, that of the women who apply for charity in the treatment of tuberculosis nearly one-half are houseworkers. The number of women who applied for treatment is eight hundred and fifty-one and the number of houseworkers is three hundred and sixty. The other female occupations most numerously represented in the table are, in respective order: factory hand, forty-seven; weaver, thirty-two; seamstress, thirty-three; laundry-worker, fourteen; store employee, twelve; and nurse, seven. Some of these occupations are pursued by men as well as women. The occupation of seamstress is the only one exclusively filled by women. With this occupation the question of remuneration plays a part. Seamstresses are poorly paid and are compelled to work in unhygienic environments.

The male occupation which stands at the head of the list is that of laborer, with one hundred and one. The laborer is not only poorly paid, and consequently poorly fed, but lives in poor environments. He has more chance of having the disease in his home than most people, by reason of his poverty, and consequently he is more apt to be exposed to contagion than most people. A group of occupations all belonging to the same category is that of tailor with fifty-nine; that of clerk with forty-three; that of cigarmaker with thirty; that of salesman with thirteen; that of printer with fourteen; and that of shoemaker with twelve. In all of these occupations there is poor pay, which means deprivation at home, and bad sanitary conditions in the place of occupation. Another group is that in which alcohol plays a part; those occupations in which, by reason of association, exposure, or hard work, there is a temptation to use alcohol in some form or other. To this group belongs the occupation of driver with forty-two; that of waiter with twenty-one; bartender with fourteen; plumber with ten; and cook with ten. In these occupations neither want of food nor lack of fresh air plays a part. There is usually plenty to eat and there is either outdoor life or fair indoor

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environment. The propensity to tuberculosis in these cases is due to alcoholism. In these occupations the temptation and opportunity for the use of alcohol are great. Another group is that in which occupation exposes to inhalation of irritating substances given off in manufacturing processes. These irritating substances may act in two ways, one as a medium of contagion, the other as a means of traumatism. They probably act in both ways. To this group belongs the occupation of mill-hand with sixty-four; machinist with thirty-five; weaver with thirty-two; iron-worker with twenty-one; upholsterer with nine; and leatherworker with nine. The high morbidity in some of the occupations is only intelligible upon the assumption that the occupations were taken up after the disease had been contracted, because the occupations are easy and out-of-doors. Such are, for example, the occupations of canvasser, agent, collector, and peddler. The occupation of car conductor, I know, is frequently taken up by persons who have had tuberculosis and who have made a partial recovery.

ALCOHOLISM

In former times alcohol was looked upon as a preventive and cure of tuberculosis. At the present day alcohol is looked upon as a predisposing cause of the disease and as an impediment to recovery. Neither of these views apparently gets much support from the statistics here given. The word “alcoholism" as here used means an excessive use of alcohol, but not necessarily a use of alcohol to the degree of drunkenness. A person was not put down as an alcoholic unless he used enough alcohol to do himself some physical harm. Of course, it is not easy to get a history of alcoholism from a patient, and some allowance must be made on this score for the smallness of the numbers. As the figures stand, however, the percentage of alcoholics among consumptives and among the relatives of consumptives does not

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seem to differ very much from that of nonconsumptives and relatives of nonconsumptives.

PREDISPOSING DISEASES.

It has been held that certain diseases greatly predispose to tuberculosis. This view has originated from the observation that these diseases frequently precede tuberculosis within a few years, and sometimes within a few months. The diseases which have best earned this reputation are typhoid fever, pneumonia, and pleurisy. The figures would seem to indicate that pleurisy most frequently precedes tuberculosis, pneumonia next, and typhoid fever last. More than one-half the cases were preceded by one or the other of these diseases. There is good reason to believe that the pleurisies, pneumonias, and typhoid fevers which precede tuberculosis frequently are tuberculosis which goes unrecognized and simulates the diseases named. Some observers even claim that practically all pleurisies are tuberculous. That irregular forms of pneumonia and typhoid fever often are tuberculosis cannot be doubted.

SOURCE OF CONTAGION.

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An earnest effort has been made in history-taking to discover the source of contagion of each case. In the majority of cases this was made out to the extent, at least, of finding a known source of contagion. In many cases, however, owing to the ignorance and prejudice of patients and their inability to understand and speak the English language, it was impossible to get a satisfactory history. The histories of exposure to contagion which could be gotten emphasize in a striking manner the part which family relationship plays in the spread of tuberculosis. With this picture before one, it is easy to understand why the ancients looked upon tuberculosis as an inherited disease. More than two-thirds of the cases in which a history of exposure to contagion could be obtained gave contagion from blood relatives as the source of the disease. The number of cases in which the disease was derived from consorts or from members of their families is surprisingly large, and the number of cases which gave fellowemployees and infected houses as the source of contagion is surprisingly small. Of course, it must not be lost sight of that family contagion is always the most evident and easily recognized and that the large number of cases in which the source of contagion remained undiscovered were in all probability cases of occupation and house contagion. These forms of contagion are sometimes difficult to ferret out even with intelligent observing people, because one cannot always know when he is working with a consumptive or when the home into which he moves has been occupied by a consumptive. Some of the patients gave histories of double and even triple exposure.

PLACE OF BEGINNING OF TUBERCULOSIS OF THE LUNGS.

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An effort has been made to determine in what part of the lungs the disease began. The conclusions here recorded were reached by trying to determine on which side the disease had made the greatest ravages. The side which had the most extensive lesion was recorded as the side on which the disease began. This cannot always be accepted as a safe deduction. Neither can it be said that the observations upon which these records are based are entirely reliable. The records, however, strongly support the universally accepted view that the right lung is most frequently the first affected.

TISSUE INVOLVED.

A fair picture of the stages of tuberculosis in which patients applied for treatment is presented in this table. The picture is underdrawn rather than overdrawn. In the beginning of the service incomplete records were made. Of the dispensary patients more than one-half had both lungs involved and about onethird were far advanced in the disease. Of the hospital patients only a little over 7 % had the disease limited to one lung. All this shows how slow people with tuberculosis are to recognize that they are ill and need medical attendance. Tuberculosis is such an insidious disease that it makes great progress before its existence is even suspected by the victim.

FREEDOM FROM COUGH.

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It is usually taken for granted that cough is an essential symptom of pulmonary tuberculosis. Cough is a usual symptom, but not an essential one. It may be absent in tuberculous patients and it may be present in nontuberculous patients. Forty-one patients who were diagnosed as having tuberculosis were free from cough. At rest, with proper regulation of diet, tuberculous patients cough very little. In the hospital no cough medicines are used, and although the patients all are advanced, many with both lungs extensively diseased, there is very little coughing.

TUBERCLE BACILLI IN SPUTUM.

Many sputum examinations were not recorded. This was on account of the constant pressure of work. Of the cases recorded, a little less than two-thirds showed the presence of tubercle bacilli in a limited number of examinations. This gives a fair picture of the frequency with which sputum of tuberculous patients is negative. One or two examinations, when negative, mean very little. Tubercle bacilli may be absent from the sputum upon repeated examinations even in advanced cases. This was demonstrated in some of the cases which came to autopsy. A negative report on sputum, even when repeated examinations have been made, should not be allowed to stand against positive clinical evidence of tuberculosis in making a diagnosis. It is only when the clinical symptoms agree with the negative report of the sputum that a negative diagnosis should be made.

HOARSENESS.

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Hoarseness in tuberculosis is not necessarily an indication of laryngeal tuberculosis even when the hoarseness is persistent. Usually persistent hoarseness does mean laryngeal tuberculosis. Tuberculosis of the pharynx and tonsils occurs pretty often in advanced stages of the disease and sometimes accounts for persistent hoarseness. Mixed infection alone may be responsible for this symptom, however. Chronic catarrhal rhinitis and pharyngitis occur frequently in tuberculosis and sometimes keep up hoarseness for a long time.

DISEASES OF THE CIRCULATORY SYSTEM. These statistics upon lesions and functional diseases of the circulatory system, it must be admitted, cannot be accepted as giving an accurate picture of the frequency with which such conditions occur in tuberculosis. It requires great skill and large clinical experience to make exact trustworthy records of organic heart lesions. Such skill and experience cannot be claimed for the medical staff in the beginning of the work, at least. In many cases, moreover, no record was made at all of the condition of the circulatory system. Even in the matter of functional disturb-

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ances, such as accentuated second sound, the record is very incomplete. Some of the members of the staff recorded accentuated second sound in a majority of the patients and others recorded it in almost none. Neither was there always a distinction made between accentuation of the aortic second sound and the accentuation of the pulmonic second sound. This kind of work is more accurately done now than it was in the beginning, so that future statistics will throw more light upon the subject.

URINARY ABNORMALITIES.

Although it is part of the program of the Institute to make a careful urinary analysis of all patients who apply for treatment, little was accomplished in this line during the first year. Many examinations which were made were not recorded, and there is no way of determining the number of cases on which this table is based. Our shortcomings were due principally to the heavy pressure under which we have worked from the beginning and to the lack of facilities for such work.

GENITO-URINARY DISEASE.

The statistics here given, it must be frankly admitted, are unreliable. In many cases the thorough investigation necessary for determining whether or not there was genito-urinary involvement was not made. It is not an easy matter to determine clinically whether or not such organs are tuberculous. The symptoms which may indicate genito-urinary tuberculosis may also

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indicate other diseases, and it is sometimes impossible to differentiate. Besides, in the cases in which genito-urinary disease is recorded there is no record as to whether or not the genito-urinary diseases were tuberculous in character.

HEMOPTYSIS.

It is rather surprising that so large a percentage of cases gave a history of hemoptysis. This same ratio probably would not hold with people better situated in life. Hemoptysis undoubtedly is largely due to overexertion. The pulmonary circulation becomes embarrassed by reason of obstruction and the heart is stimulated to greater effort. Bodily fatigue adds to this overaction, and with contraction of the blood-vessels hemorrhage The patients who entered the hospital and were placed at rest remained almost free from hemorrhages even in the advanced stages.

NIGHT-SWEATS.

In practically all of the patients in the hospital the nightsweats stopped after the patient had been at rest for awhile and had had his diet regulated. No drugs are used in the hospital for night-sweats and none are necessary. The large number of cases with night-sweats both in the hospital and dispensary indicates how advanced many of the patients were when they came under treatment. It also shows how few patients with tuberculosis come under treatment early.

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DIARRHEA.

Of the patients with persistent diarrhea, fifty were in the hospital. Persistent diarrhea in a tuberculous patient usually indicates that the patient has tuberculous ulceration of the bowels. Sometimes, however, extensive ulceration of the bowels exists without much disturbance of the bowels; and sometimes great disturbance of the bowels exists without ulceration.

EDEMA.

Edema in tuberculosis usually is the result of damaged circulation following in the wake of the tuberculous process in the lungs and other organs. Right-sided dilatation of heart with consequent dilatation of the left heart occurs frequently in advanced tuberculosis. This no doubt plays a part in edema. Tuberculosis of the kidneys, however, probably also plays a part. The kidneys frequently become the seat of tuberculosis. The records as given here probably understate the percentage of cases in which edema occurs in tuberculosis. In many cases no careful investigation was made for edema and no records were kept.

DURATION OF DISEASE.

The records here given understate the actual duration of the disease. It takes considerable experience to be able to bring

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out the full duration of tuberculosis when taking the history of a case. In our first year's work there has been a continuous increase in the duration of disease as the experience of our men grew in taking histories. Patients, as a rule, fix the beginning of the disease by the first severe break in health. As a matter of fact, the beginning of tuberculosis gives no symptoms. Very often even a number of serious interferences with health, recurring at intervals of three to six months, may take place before suspicion points to what is the matter. Tuberculosis exists from the time of implantation, and the duration of the disease really should be counted from the time of exposure to contagion.

WEIGHT.

The weights given in this table are net weights. When a patient gained and then lost, only that which he held was counted; and when a patient lost and then gained, only the gain above

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what he weighed when he began treatment was counted. In the same way the losses were based upon the weight when treatment began.

Weight is a criterion of the progress of tuberculosis up and down. Loss of weight undoubtedly is one of the results of tuberculous toxemia. One of the first evidences of deterioration is loss of weight. An early sign of improvement in a tuberculous patient, on the other hand, is gain in weight. While this is the rule, there are exceptions. Tuberculosis may terminate fatally without emaciation. A person with tuberculosis may be so fed up as to become quite rounded and well filled out and still go on to death. In these cases death is usually due to complications of one kind or another. Sometimes so many organs have been damaged by the tuberculous process that life is snuffed out by a simple cold. This is especially true when the kidneys are extensively diseased.

Both in the dispensary and in the hospital there were some very large gains. Along with these gains went general improvement and progress toward recovery. The highest gain in the hospital was thirty-three and one-half pounds. The greatest loss in the hospital was twenty-five and three-quarter pounds. The highest gain in the dispensary was thirty-nine pounds and the greatest loss in the dispensary was thirty and one-quarter pounds.

RESULTS OF TREATMENT.

The word improved is here used to indicate any amelioration of symptoms with increase in weight and gain in physical health--

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one or both. The improvement in some cases was very marked, and this applies even to advanced cases. Some of the patients who came into the hospital as advanced cases were restored to a condition of physical health which enabled them to return to their occupations. Unimproved includes all cases in which there was no perceptible progress toward recovery. Even patients who gained weight for awhile and lost it again, were recorded as unimproved. The cases recorded as unimproved sometimes were lost sight of, either by removal from the hospital or by giving up treatment at the dispensary. Many of them no doubt died. The record of deaths in the dispensary, and in a less degree in the hospital, for this reason, has little value.

SPECIAL WORK.

For the purpose of studying tuberculosis from every possible point of view and giving relief in all forms of the disease, special departments have been established in the Institute and others will be established as the work develops. Up to the present time there have been organized a neurological staff, a laryngological staff, and a dermatological staff. The laboratory, both in its bacteriological department and in its pathological department, has been established and partly equipped, but not fully organized. A consulting ophthalmologist has been appointed on the staff. Separate reports on laryngological and neurological work are made by Drs. Geo. B. Wood and D. J. McCarthy. Dr. Joseph Walsh reports upon the autopsies and Dr. M. P. Ravenel upon a case of fibroid phthisis. Drs. H. R. M. Landis and J. W. Irwin report special work assigned by the medical director.

PREVENTION OF TUBERCULOSIS.

One of the objects of the Institute is the prevention of tuberculosis. What has been accomplished during the year in this direction cannot be recorded, because it cannot be measured. The patients who have been taken into the hospital have been taken out of squalid, poverty-stricken homes, where they had

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been sources of danger to others. The probabilities are that every removal of such a patient has been the means of preventing at least one implantation. Even when the patient returned again to his home, something had been accomplished, because he went home trained in preventive measures. All the dispensary patients are taught and drilled in preventive measures. As each patient comes into the waiting-room he is handed a spit-cup, and during his stay is taught to use it. When he goes away he is given a tin spit-cup holder, a bundle of paper cups, and a bundle of paper napkins and paper bags to take home with him. He is also given a set of rules on a large cardboard to hang up in his house, and on a folder to carry in his pocket. Every time he comes back to the dispensary he is given a new supply of preventive measure material, and is further instructed in its use. At regular intervals he is visited in his home by a pupil nurse and is given such instruction and assistance as he may need for prevention of the spread of the disease.

FOOD.

In the hospital all patients are placed upon a carefully selected diet. This consists of milk, eggs, and plain nutritious food. As a rule, patients take three quarts of milk and six raw eggs a day and one meal of solid food. This meal consists of beef or mutton, fresh vegetables, and fruit. To the dispensary patients milk is served at their homes from the Institute wagon or through milkmen. In the beginning all milk was served through milkmen. This system of serving through milkmen was not found satisfactory, first because the Institute could not control the quality of the milk, and secondly because the system was open to fraud. As an experiment the Institute has equipped a milk wagon of its own.

MEDICINE.

To the house patients all medicine is furnished free. To the dispensary patients it is furnished either free or at a nominal

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cost. A nominal charge, consisting of twenty-five cents for one prescription, forty cents for two prescriptions, and fifty cents for three or more prescriptions to one and the same person at the same time, is made to such patients as can afford it, for two reasons: first, to give them a semblance of independence; and, secondly, to discourage as far as possible unnecessary drugtaking. The majority of dispensary patients are, however, unable to maintain even this little pretense of self-support.

SCIENTIFIC RESEARCH.

The study of tuberculosis is one of the purposes of the Institute. For this reason a laboratory and pathological museum and an autopsy room have been equipped. In the crowded, cramped quarters of the Institute in its temporary home, it has been difficult to carry out this purpose. Something has been accomplished, however. Nearly all patients who have died have been carefully autopsied; a valuable collection of pathological specimens has been collected; many sections have been made for microscopic study, and a beginning has been made in laboratory research. The staff meets weekly for scientific discussion and exchange of thought. All work done is carefully scrutinized and criticized at these meetings.

EDUCATIONAL WORK.

Early in the Institute's first year an international lecture course on tuberculosis was got up for the education of the public. Prominent workers from different parts of the world were brought to Philadelphia to speak to the world from a Philadelphia platform. The lectures delivered on these occasions were published in the medical journals and in abstract in the daily papers. They are republished as part of this first annual report, although all of them were not delivered within the first year.

The lecturers were Drs. E. L. Trudeau, of Saranac; Wm. Osler, of Baltimore; G. Sims Woodhead, of Cambridge, England;

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Herman M. Biggs, of New York; and Edoardo Maragliano, of Italy. Dr. Trudeau, the pioneer worker in the field of tuberculosis in America, opened the course. He was followed by the other gentlemen in the order named. Dr. Maragliano was prevented from coming to America at the last moment by serious personal illness, but his paper was read at the time set for his appearance and was subsequently published. The course of lectures was well attended and the publication of the lectures has stimulated much activity in the warfare against the disease. On the occasion of Dr. Maragliano's lecture the National Association for the Study and Prevention of Tuberculosis was organized.

THE FIRST YEAR'S HARVEST.

To organize a new work is a difficult undertaking. The Henry Phipps Institute for the Study, Treatment, and Prevention of Tuberculosis is in its conception and establishment an embodiment of a new idea-namely, concentrated effort upon a single disease for its extermination. The financial resources were at hand through the generosity of Mr. Henry Phipps, but there was no precedent for the creation of machinery and the formation of the line of battle. Everything had to be worked out and tested. Classical prejudices of all kinds and complexions stood in the way. The line of action lay in opposition to preconceived notions and the teaching of medicine for generations. Weighed in the balance of these difficulties, the harvest of the first year's labor has been good. In addition to what has been accomplished in treatment, prevention, and education, there has been some golden fruit in the training of medical experts and special nurses. This perhaps is the best of the Institute's work. The training of women for the care of tuberculous subjects and the creation of a new field of labor for women who have had tuberculosis and have recovered, perhaps, would be worth the labor and money which have been expended. These women become missionaries in the crusade against tuberculosis.

LAWRENCE F. FLICK.